Department of Neurology, Laboratory of Clinical Neurophysiology, Zvolen Hospital, Zvolen, Slovak Republic.
Physiol Res. 2020 Apr 30;69(2):331-337. doi: 10.33549/physiolres.934066.
Based on the fact that tremors display some distinct 3D spatial characteristics, we decided to visualise tremor planes in 3D space. We obtained 3-axial linear accelerometer signals of hand tremors from 58 patients with Parkinson´s disease (PD), 37 with isolated resting tremor (iRT), 75 with essential tremor (ET), and 44 healthy volunteers with physiological tremor (Ph). For each group analysis was done with subsequent spatial 3D regression of the input data i.e. along the x, y and z axes; the projected vector lengths in the individual (vertical transversal XY, vertical longitudinal XZ and horizontal YZ) reference frame planes and their angles. Most meaningful and statistically significant differences were found in the analyses of the 3D vector lengths. The tremor of the PD and the iRT group was oriented mainly in the horizontal YZ plane. The tremors of the patients with ET and Ph were oriented approximately in the midway between the all three referential planes with less tilt toward the vertical longitudinal XZ plane.
基于震颤表现出一些明显的三维空间特征这一事实，我们决定将震颤平面可视化在三维空间中。我们从 58 名帕金森病（PD）患者、37 名孤立性静止性震颤（iRT）患者、75 名特发性震颤（ET）患者和 44 名生理性震颤（Ph）的健康志愿者中获得了手部震颤的三轴线性加速度计信号。对于每个组，我们都通过输入数据的后续空间 3D 回归进行了分析，即沿着 x、y 和 z 轴；在个体（垂直横向 XY、垂直纵向 XZ 和水平 YZ）参考系平面中和它们的角度上的投影向量长度。在 3D 向量长度的分析中发现了最有意义和最显著的差异。PD 和 iRT 组的震颤主要定向在水平 YZ 平面中。ET 和 Ph 患者的震颤大约定向在所有三个参考平面的中间，向垂直纵向 XZ 平面的倾斜度较小。
