Daga Subhashchandra, Mhatre Sameer, Borhade Anushree, Khan Danish
Department of Pediatrics, Maharashtra Institute of Medical Education and Research (MIMER) Medical College, Talegaon Dabhade, Pune 410507, India
Department of Pediatrics, Maharashtra Institute of Medical Education and Research (MIMER) Medical College, Talegaon Dabhade, Pune 410507, India.
J Trop Pediatr. 2014 Oct;60(5):343-7. doi: 10.1093/tropej/fmu023. Epub 2014 Apr 23.
To study the effectiveness of locally assembled low-cost version for continuous positive airway pressure (CPAP) delivery.
Babies with respiratory distress from two contiguous periods, one with CPAP therapy and the other without, were compared for following parameters: birth weight, gestational age, severity of respiratory distress, as assessed by Silverman-Anderson retraction score (SARS), maximum SARS, days taken for score to become 0, duration of oxygen therapy, hospital stay and the outcome.
The profile of subjects was comparable in two groups. Severity of respiratory distress (SARS) was significantly higher in post-CPAP group. Time taken for SARS to become 0 and number of deaths were significantly lower, and the duration of oxygen administration and hospital stay were significantly higher in post-CPAP group. The cost of an individual disposable CPAP unit was ∼Rs 160 (USD 3).
A low-cost and locally assembled CPAP delivery system may reduce neonatal mortality among babies with respiratory distress.
研究本地组装的低成本持续气道正压通气（CPAP）设备的有效性。
选取两个连续时间段内患有呼吸窘迫的婴儿，一组接受CPAP治疗，另一组未接受，比较以下参数：出生体重、胎龄、呼吸窘迫严重程度（通过Silverman-Anderson凹陷评分（SARS）评估）、最大SARS评分、评分降至0所需天数、氧疗持续时间、住院时间及转归。
两组受试者情况具有可比性。CPAP治疗后组的呼吸窘迫严重程度（SARS）显著更高。CPAP治疗后组SARS评分降至0所需时间及死亡人数显著更低，而氧疗持续时间和住院时间显著更长。单个一次性CPAP设备的成本约为160卢比（3美元）。
低成本的本地组装CPAP设备可能降低患有呼吸窘迫婴儿的新生儿死亡率。
