来自缺陷假单胞菌和泡囊假单胞菌的脂多糖A制剂的表位分析。
Epitope analysis of lipid A preparations from Pseudomonas diminuta and Pseudomonas vesicularis.
作者信息
Arata S, Hirayama T, Akiyama Y, Mashimo J, Kasai N, Yoshida K, Nakamura Y, Aoki Y
机构信息
Department of Microbial Chemistry, School of Pharmaceutical Sciences, Showa University, Tokyo, Japan.
出版信息
FEMS Microbiol Lett. 1989 Jul 15;51(1):223-5. doi: 10.1016/0378-1097(89)90513-2.
In vitro antigenic reactivity of lipid A from Pseudomonas diminuta and Pseudomonas vesicularis with homologous and heterologous lipid A antibodies including monoclonal antibodies was studied by inhibition test of enzyme-linked immunosorbent assay (ELISA). The results suggest that both Pseudomonas lipid As have very similar epitopes, including species-specific and cross-reactive epitopes as compared with enterobacterial lipid A.
通过酶联免疫吸附测定（ELISA）抑制试验，研究了来自缺陷假单胞菌和泡囊假单胞菌的脂多糖A与同源和异源脂多糖A抗体（包括单克隆抗体）的体外抗原反应性。结果表明，与肠杆菌脂多糖A相比，两种假单胞菌脂多糖A具有非常相似的表位，包括种特异性表位和交叉反应表位。
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