Farag I S Ahmed, Girgis Adel S, Ramadan A A, Moustafa A M, Tiekink Edward R T
Solid State Department, Physics Division, National Research Centre, Dokki, Giza, Egypt.
Pesticide Chemistry Department, National Research Centre, Dokki, Giza 12622, Egypt.
Acta Crystallogr Sect E Struct Rep Online. 2013 Dec 18;70(Pt 1):o70-1. doi: 10.1107/S1600536813033771. eCollection 2014 Jan 1.
The title compound, C34H38ClN5O2, has spiro links connecting the pyrrolidine ring and indole residue, as well as the piperidine and pyrrolidine rings. A half-chair conformation is found for the piperidine ring with the C atom connected to the spiro-C atom lying 0.738 (4) Å out of the plane of the remaining five atoms (r.m.s. deviation = 0.0407 Å). The methyl-ene C atom is the flap in the envelope conformation for the pyrrolidine ring. In the crystal, supra-molecular chains are sustained by alternating eight-membered {⋯HNCO}2 and 14-membered {⋯HC5O}2 synthons. Chains are connected into a three-dimensional network by (pyrrolidine-bound phenyl-meth-yl)C-H⋯π(pyrrolidine-bound phen-yl) edge-to-face inter-actions.
标题化合物C₃₄H₃₈ClN₅O₂具有连接吡咯烷环与吲哚残基以及哌啶环与吡咯烷环的螺环连接。哌啶环呈半椅式构象,与螺碳相连的C原子偏离其余五个原子平面0.738 (4) Å(均方根偏差 = 0.0407 Å)。亚甲基C原子是吡咯烷环信封式构象中的瓣。在晶体中,超分子链由交替的八元{⋯HNCO}₂和十四元{⋯HC₅O}₂合成子维持。链通过(吡咯烷连接的苯甲基)C—H⋯π(吡咯烷连接的苯基)面对面相互作用连接成三维网络。