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睾丸腺瘤样瘤:两例报告并文献复习

Adenomatoid tumors of the testis: A report of two cases and review of the literature.

作者信息

Chen Duqun, Yu Zuhu, Ni Liangchao, Gui Yaoting, Yang Shangqi, Shi Bentao, Lai Yongqing

机构信息

Department of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen 518036, P.R. China ; The Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen 518036, P.R. China ; Anhui Medical University, Hefei, Anhui 230032, P.R. China.

Department of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen 518036, P.R. China ; The Guangdong and Shenzhen Key Laboratory of Male Reproductive Medicine and Genetics, Institute of Urology, Peking University Shenzhen Hospital, Shenzhen PKU-HKUST Medical Center, Shenzhen 518036, P.R. China.

出版信息

Oncol Lett. 2014 May;7(5):1718-1720. doi: 10.3892/ol.2014.1938. Epub 2014 Mar 5.

DOI:10.3892/ol.2014.1938
PMID:24765207
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3997688/
Abstract

Adenomatoid tumors are rare benign neoplasms that normally occur in the scrotum. The clinical symptoms and routine examinations mean that it is difficult to distinguish adenomatoid tumors from malignant intratesticular solid tumors, which may result in unnecessary orchidectomies. The present report describes two adenomatoid tumor patients treated between 2006 and 2013 at the Peking University Shenzhen Hospital who presented with an asymptomatic mass in the scrotum. Based on thorough analysis of clinical features, blood, radiological images and intra-operative findings, limited local excisions were performed, revealing adenomatoid tumors of the testis on pathological examination. The patients were followed up and exhibit no recurrence at the time of writing. The present report also summarizes the morphological and immunohistochemical features of paratesticular tumors and reviews the literature to improve understanding of these rare lesions and assist in accurate diagnosis.

摘要

腺瘤样瘤是一种罕见的良性肿瘤,通常发生于阴囊。临床症状和常规检查表明,腺瘤样瘤很难与睾丸内恶性实性肿瘤区分开来,这可能导致不必要的睾丸切除术。本报告描述了2006年至2013年期间在北京大学深圳医院接受治疗的两名腺瘤样瘤患者,他们均表现为阴囊内无症状肿块。基于对临床特征、血液检查、影像学图像和术中发现的全面分析,实施了局部有限切除,病理检查显示为睾丸腺瘤样瘤。对患者进行了随访,在撰写本文时未发现复发情况。本报告还总结了睾丸旁肿瘤的形态学和免疫组化特征,并回顾了相关文献,以增进对这些罕见病变的了解并协助准确诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2e2/3997688/0a227b20355f/OL-07-05-1718-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2e2/3997688/0a227b20355f/OL-07-05-1718-g00.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a2e2/3997688/0a227b20355f/OL-07-05-1718-g00.jpg

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引用本文的文献

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Contemporary analysis of epididymal tumors using a national database.利用国家数据库对附睾肿瘤进行当代分析。
Cent European J Urol. 2021;74(1):39-43. doi: 10.5173/ceju.2021.0249.R1. Epub 2021 Feb 19.
2
Adenomatoid tumor of the testis mimicking malignant testicular cancer on multiparametric ultrasound.睾丸腺瘤样肿瘤在多参数超声上模拟恶性睾丸癌。
Eur J Med Res. 2018 Jan 11;23(1):3. doi: 10.1186/s40001-018-0301-5.
3
Epididymal Adenomatoid Tumor: A Very Rare Paratesticular Tumor of Childhood.附睾腺瘤样瘤:一种非常罕见的儿童睾丸旁肿瘤。

本文引用的文献

1
Adenomatoid tumor of testis: A rare cytological diagnosis.睾丸腺瘤样瘤:一种罕见的细胞学诊断。
J Cytol. 2013 Jan;30(1):65-7. doi: 10.4103/0970-9371.107519.
2
Imaging of the scrotum.阴囊成像
Radiol Clin North Am. 2012 Nov;50(6):1145-65. doi: 10.1016/j.rcl.2012.08.003.
3
Adenomatoid tumour of testis.睾丸腺瘤样瘤
Case Rep Med. 2016;2016:9539378. doi: 10.1155/2016/9539378. Epub 2016 Nov 27.
BMJ Case Rep. 2011 Mar 8;2011:bcr0120113790. doi: 10.1136/bcr.01.2011.3790.
4
Can radical orchiectomy be avoided for paratesticular adenomatoid tumor?睾丸旁腺瘤样瘤能否避免根治性睾丸切除术?
Indian J Urol. 2011 Oct;27(4):556-7. doi: 10.4103/0970-1591.91454.
5
Adenomatoid tumor of the testis with intratesticular growth: a case report and review of the literature.
Int J Surg Pathol. 2011 Dec;19(6):838-42. doi: 10.1177/1066896911398656. Epub 2011 Mar 21.
6
[Rare case of multiple adenomatoid tumors arising from tunica vaginalis of testis and epididymis].
Actas Urol Esp. 2010 Jun;34(6):560-1.
7
Adenomatoid tumor of tunica albuginea mimicking seminoma on fine needle aspiration cytology: a case report.白膜腺瘤样瘤在细针穿刺细胞学检查中误诊为精原细胞瘤:一例报告
Acta Cytol. 2009 May-Jun;53(3):349-52. doi: 10.1159/000325324.
8
Intraparenchymatous adenomatoid tumor dependent on the rete testis: A case report and review of literature.依赖睾丸网的实质内腺样瘤:1例报告并文献复习
Indian J Urol. 2009 Jan;25(1):126-8. doi: 10.4103/0970-1591.45551.
9
Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors.其他选定的有问题的睾丸和睾丸旁病变:睾丸网肿瘤和假瘤、间皮病变及继发性肿瘤。
Mod Pathol. 2005 Feb;18 Suppl 2:S131-45. doi: 10.1038/modpathol.3800314.
10
Adenomatoid tumors of the female and male genital tracts express WT1.女性和男性生殖道的腺瘤样瘤表达WT1。
Int J Gynecol Pathol. 2004 Apr;23(2):123-8. doi: 10.1097/00004347-200404000-00006.