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高安动脉炎中主动脉及左冠状动脉主干瘤与严重主动脉瓣关闭不全的关联。

Association of aortic and main left coronary aneurysms with severe aortic insufficiency in Takayasu's arteritis.

作者信息

Schafranski Marcelo Derbli, Ferraz de Freitas Marcelo, Valladão de Carvalho Marcelo

机构信息

Department of Rheumatology;

Department of Cardiovascular Surgery;

出版信息

Clin Pract. 2011 Apr 22;1(2):e26. doi: 10.4081/cp.2011.e26. eCollection 2011 May 16.

Abstract

Takayasu's arteritis is a granulomatous vasculitis of unknown etiology that affects mainly the aorta and its branches. As a result of intimal fibroproliferation, segmental stenosis, occlusion, dilatation, and aneurysmal formation of the involved vessels may develop. It is an uncommon disease and usually affects young Asian female patients during the second and third decades of life. Coronary arteries are exceptionally affected and coronary aneurysm formation is a very rare finding. We describe a case of a previously healthy 26-year-old Caucasian female whose Takayasu's arteritis presented as a previously undescribed association of aortic and main left coronary aneurysms with severe aortic insufficiency.

摘要

高安动脉炎是一种病因不明的肉芽肿性血管炎,主要累及主动脉及其分支。由于内膜纤维增生,受累血管可能会出现节段性狭窄、闭塞、扩张和动脉瘤形成。这是一种罕见疾病,通常在青年期(二三十岁)影响年轻的亚洲女性患者。冠状动脉极少受累,冠状动脉瘤形成是非常罕见的表现。我们描述了一例既往健康的26岁白种女性,其高安动脉炎表现为主动脉瘤和左冠状动脉主干瘤合并严重主动脉瓣关闭不全,这种情况此前未曾有过描述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38e9/3981242/0cdecbdf013c/cp-2011-2-e26-g001.jpg

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