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高安动脉炎:综述

Takayasu arteritis: a review.

作者信息

Johnston S L, Lock R J, Gompels M M

机构信息

Department of Immunology and Immunogenetics, Southmead Hospital, Westbury on Trym, Bristol BS10 5NB, UK.

出版信息

J Clin Pathol. 2002 Jul;55(7):481-6. doi: 10.1136/jcp.55.7.481.

Abstract

Takayasu arteritis is a well known yet rare form of large vessel vasculitis. This review details the history, clinical features, differential diagnoses, classification, and immunology of the disorder. Suppression of inflammation and preservation of vascular competence are the aims of treatment. As with any rare disease, randomised controlled treatment trials are either lacking or based on small patient numbers, making management decisions difficult. Current evidence based treatments are presented and discussed.

摘要

高安动脉炎是一种广为人知但罕见的大血管血管炎。本文综述详细介绍了该疾病的病史、临床特征、鉴别诊断、分类及免疫学。治疗的目的是抑制炎症并维持血管功能。与任何罕见病一样,随机对照治疗试验要么缺乏,要么基于少量患者,这使得治疗决策变得困难。本文展示并讨论了当前基于证据的治疗方法。

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