一名早期乳腺癌患者在接受多西他赛治疗后出现严重肌痛，随后因产气荚膜梭菌引发暴发性感染性休克。
Fulminating septic shock from Clostridium perfringens in an early breast cancer patient with severe myalgia after docetaxel treatment.
作者信息
Minisini Alessandro Marco, Menis Jessica, Follador Alessandro, Avellini Claudio, Fasola Gianpiero
机构信息
Department of Oncology and.
Department of Pathology, University and General Hospital of Udine, Italy.
出版信息
Clin Pract. 2011 May 12;1(2):e33. doi: 10.4081/cp.2011.e33. eCollection 2011 May 16.
Abstract
Anaerobic bacteraemia could be a life-threatening condition in neutropenic patients receiving chemotherapy. Taxane therapy is associated with necrotising inflammation of the caecum (named also typhlitis) that could be a potential source for bacteraemia. We report the case of a sudden onset of septic shock by Clostridium perfringens in a young patient treated with docetaxel as adjuvant chemotherapy for early breast cancer. A mini-review of the literature has been performed.
摘要
厌氧菌血症对于接受化疗的中性粒细胞减少患者而言可能是一种危及生命的病症。紫杉烷疗法与盲肠坏死性炎症（也称为盲肠炎）相关，而盲肠炎可能是菌血症的一个潜在来源。我们报告了一例年轻患者的病例，该患者在接受多西他赛辅助化疗治疗早期乳腺癌时突然发生产气荚膜梭菌所致的感染性休克。我们还对相关文献进行了简要综述。
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