Juergenson Ina, Mazzucco Sara, Tinazzi Michele
Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, Italy.
Clin Pract. 2011 Nov 18;1(4):e114. doi: 10.4081/cp.2011.e114. eCollection 2011 Sep 28.
Watershed infarcts (WI) evolve in hemodynamic risk zones. Clinical picture of WI can be associated to partial epileptic seizures. Diffusion weighted brain magnetic resonance imaging (MRI) allows a clear diagnosis. WI pathogenesis involves either embolic or hemodynamic mechanism. A 69-year old patient presented with sub-acute occurrence of right hemiparesis and partial epileptic seizures of the right arm. Carotid ultrasounds demonstrated occlusion of the right extra-cranial internal carotid artery (ICA) and tight stenosis of the contralateral ICA. Brain Diffusion-Weighted magnetic resonance revealed acute ischemic lesions within the watershed area of the left hemisphere. Our case supports the hypothesis of impaired washout of emboli in low-perfusion brain areas as the mechanism underlying cortical WI.
分水岭梗死(WI)发生于血流动力学风险区域。WI的临床表现可能与部分癫痫发作有关。弥散加权脑磁共振成像(MRI)可明确诊断。WI的发病机制涉及栓塞或血流动力学机制。一名69岁患者出现亚急性右半身轻瘫和右臂部分癫痫发作。颈动脉超声显示右侧颅外颈内动脉(ICA)闭塞,对侧ICA严重狭窄。脑弥散加权磁共振显示左半球分水岭区域内有急性缺血性病变。我们的病例支持这样一种假说,即低灌注脑区栓子清除受损是皮质WI的潜在机制。