Akhtar Kafil, Sherwani Rana, Anees Afzaal
Departments of Pathology and.
Surgery, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh (U.P), India.
Clin Pract. 2012 May 7;2(2):e53. doi: 10.4081/cp.2012.e53. eCollection 2012 Mar 30.
This report describes the case of a 50-year-old female patient who presented with bilateral adnexal lump and dysfunctional uterine bleeding with altered bowel habits. Computed tomography of the abdomen and pelvis revealed a bilateral adnexal lump situated in both the ovaries and a lobular mass of 8 cm in the rectum. Proctoscopy revealed an elevated irregular rectal lesion. The microscopic examination of the ovarian lump revealed a bilateral serous adenocarcinoma with a papillary pattern with psammomatous calcification. A left hemicolectomy with lymphadenectomy was also performed. Immunohistochemical staining was positive for cytokeratin 7 and negative for cytokeratin 20. The use of immunohistochemistry demonstrated the tumor to be of ovarian origin. We report this case of synchronous involvement of the ovary and the colorectum because of its rarity and unusual presentation.
本报告描述了一名50岁女性患者的病例，该患者表现为双侧附件肿块、功能失调性子宫出血以及排便习惯改变。腹部和盆腔计算机断层扫描显示双侧附件肿块位于双侧卵巢，直肠有一个8厘米的小叶状肿块。直肠镜检查发现直肠病变隆起且不规则。卵巢肿块的显微镜检查显示为双侧浆液性腺癌，呈乳头状模式并伴有砂粒体钙化。还进行了左半结肠切除术及淋巴结清扫术。免疫组化染色细胞角蛋白7呈阳性，细胞角蛋白20呈阴性。免疫组化的应用表明该肿瘤起源于卵巢。我们报告此例卵巢和结肠直肠同时受累的病例，因其罕见且表现不寻常。
