Sheen Tzong-Chyi, Lu Ming-Huei, Lee Mei-Yu, Chen Su-Ru
Department of Obstetrics and Gynecology, Yuan's General Hospital, No. 162, Chenggong 1st Rd., Kaohsiung 802, Taiwan.
Ann Noninvasive Electrocardiol. 2014 May;19(3):273-8. doi: 10.1111/anec.12139.
Nonreassuring fetal status (NRFS) refers to a compromised fetal condition which implies hypoxia. The influence of intrapartum hypoxia on autonomic nervous system function in early postnatal life is unknown. This study explored the influence of NRFS on the heart rate variability (HRV) of newborn infants.
Singleton newborn infants delivered through Cesarean delivery (CD) with indications of elective purpose (n = 32), dystocia (n = 29), or NRFS (n = 22), and through vaginal birth (VB) (n = 80) were consecutively collected. HRV parameters including standard deviation of average NN intervals (SDANN), low frequency (LF), high frequency (HF), LF%, HF%, and total power (TP), were obtained for analysis in 3 days postpartum. An independent t-test or one-way ANOVA was used to compare differences in numeric data.
SDANN, HF, HF%, and TP of newborn infants in the VB group were significantly higher than those in the CD group. The NRFS group had significantly lower SDANN, HF, and TP than those of the elective group, and significantly lower HF, HF%, and TP than those of the dystocia group.
Newborn infants delivered through Cesarean section had lower HRV, especially those who experienced NRFS during labor. The long-term effects of changes of HRV in neonates require further evaluation.
胎儿状况不良（NRFS）指胎儿状态受损，提示存在缺氧情况。产时缺氧对出生后早期自主神经系统功能的影响尚不清楚。本研究探讨了NRFS对新生儿心率变异性（HRV）的影响。
连续收集通过剖宫产（CD）分娩的单胎新生儿，其中择期剖宫产（n = 32）、难产剖宫产（n = 29）或因NRFS剖宫产（n = 22），以及经阴道分娩（VB）的新生儿（n = 80）。获取产后3天内的HRV参数，包括平均NN间期标准差（SDANN）、低频（LF）、高频（HF）、LF%、HF%和总功率（TP），进行分析。采用独立t检验或单因素方差分析比较数值数据的差异。
VB组新生儿的SDANN、HF、HF%和TP显著高于CD组。NRFS组的SDANN、HF和TP显著低于择期剖宫产组，HF、HF%和TP显著低于难产剖宫产组。
剖宫产出生的新生儿HRV较低，尤其是产时经历NRFS的新生儿。新生儿HRV变化的长期影响需要进一步评估。
