与结核病诊断技术发展相关的经济挑战。
Economic challenges associated with tuberculosis diagnostic development.
作者信息
Hanrahan Colleen F, Shah Maunank
机构信息
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe St., E6039, Baltimore, MD 21205, USA.
出版信息
Expert Rev Pharmacoecon Outcomes Res. 2014 Aug;14(4):499-510. doi: 10.1586/14737167.2014.914438. Epub 2014 Apr 28.
Abstract
Tuberculosis remains a global health crisis in part due to underdiagnosis. Technological innovations are needed to improve diagnostic test accuracy and reduce the reliance on expensive laboratory infrastructure. However, there are significant economic challenges impeding the development and implementation of new diagnostics. The aim of this piece is to examine the current state of TB diagnostics, outline the unmet needs for new tests, and detail the economic challenges associated with development of new tests from the perspective of developers, policy makers and implementers.
摘要
结核病仍然是一场全球健康危机，部分原因是诊断不足。需要技术创新来提高诊断测试的准确性，并减少对昂贵实验室基础设施的依赖。然而，存在重大经济挑战阻碍新诊断方法的开发和实施。本文的目的是审视结核病诊断的现状，概述新测试未满足的需求，并从开发者、政策制定者和实施者的角度详细说明与新测试开发相关的经济挑战。
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