Kawagishi N, Takeda I, Miyagi S, Sato K, Ohuchi N
Division of Transplantation, Reconstruction, and Endoscopic Surgery, Tohoku University Hospital, Sendai, Japan; Division of Organ Transplantation, Tohoku University Hospital, Sendai, Japan.
Division of Transplantation, Reconstruction, and Endoscopic Surgery, Tohoku University Hospital, Sendai, Japan.
Transplant Proc. 2014 Apr;46(3):675-7. doi: 10.1016/j.transproceed.2013.11.054.
The purpose of this study was to compare the quality of life of donors using the Short Form 36 (SF-36) analysis between the left and right graft periods of living donor liver transplantation.
In the left graft period (July 1991 to July 2003), 68 donors were eligible for analysis and 76 were eligible in the right graft period (August 2003 to October 2010). Nine right lobe grafts were included in the left graft period, and 52 right lobe grafts were included in the right graft period. We investigated the risks of donation and evaluated the following: blood loss, operation time, postoperative liver function, and duration of hospitalization. We also assessed quality of life in donors, who were mailed a structured questionnaire and the SF-36.
Ten of the 68 donors in the left graft period and 12 of the 76 in the right graft period had postoperative complications. Most postoperative complications were treated without surgical procedures. There was no donor death in our series. Forty-eight donors in the left graft period and 36 in the right graft period responded to our investigation. Compared with published Japanese norms in SF-36, our donors scored similar or higher than the general population in both groups. Two donors in the left graft period and one in the right graft period regretted their decisions to donate. All donors returned to normalcy.
These results suggested that the donors' quality of life was guaranteed in terms of the SF-36 investigation regardless of the donation period in our series.
本研究旨在通过简短健康调查问卷（SF - 36）分析，比较活体肝移植供体在左叶供肝期和右叶供肝期的生活质量。
在左叶供肝期（1991年7月至2003年7月），68名供体符合分析条件；在右叶供肝期（2003年8月至2010年10月），76名供体符合条件。左叶供肝期纳入9例右叶供肝，右叶供肝期纳入52例右叶供肝。我们调查了捐赠风险，并评估了以下指标：失血量、手术时间、术后肝功能及住院时间。我们还通过向供体邮寄结构化问卷和SF - 36评估了他们的生活质量。
左叶供肝期的68名供体中有10例、右叶供肝期的76名供体中有12例出现术后并发症。大多数术后并发症无需手术治疗。本研究系列中无供体死亡。左叶供肝期的48名供体和右叶供肝期的36名供体对我们的调查做出了回应。与已公布的日本SF - 36标准相比，两组供体的得分与普通人群相似或更高。左叶供肝期有2名供体、右叶供肝期有1名供体后悔自己的捐赠决定。所有供体均恢复正常。
这些结果表明，在我们的研究系列中，无论捐赠时期如何，通过SF - 36调查可知供体的生活质量得到了保障。
