Hamon C, Bizien T, Artzner F, Even-Hernandez P, Marchi V
Institut des Sciences Chimiques de Rennes, University Rennes 1, UMR 6226 C.N.R.S., Campus de Beaulieu, 35042 Rennes Cedex, France.
Institut des Sciences Chimiques de Rennes, University Rennes 1, UMR 6226 C.N.R.S., Campus de Beaulieu, 35042 Rennes Cedex, France; Institut de Physique de Rennes, University Rennes 1, UMR 6251 C.N.R.S., Campus de Beaulieu, 35042 Rennes Cedex, France.
J Colloid Interface Sci. 2014 Jun 15;424:90-7. doi: 10.1016/j.jcis.2014.03.002. Epub 2014 Mar 13.
Herein, we describe the self-assembling of gold nanorods (GNRs) induced during the ligand exchange at their surface. An exchange reaction between tricysteine PEGylated peptidic ligands and cetyltrimethylammonium bromide (CTAB)-protected gold nanorods is conducted. We demonstrated that the terminal group charge (positively or negatively charged) and the hydrophobicity of the peptidic ligands (bearing or not an undecanoyl chain) strongly affects the self-organization of the GNRs occurring in solution. Adjusting the amount of short PEGylated peptides causes a self-organization of the gold nanorods in solution, resulting in a red- or blue-shift of the plasmon bands. The decrease of their surface charge and the self-assembling in solution were first shown by zetametry, by Dynamic Light Scattering and UV-spectroscopy. Thanks to Small Angle X-ray Scattering experiments and Transmission Electron Microscopy images, the self-organization of the nanorods in solution was clearly demonstrated and correlated to the spectroscopic change in absorbance. Conversely, in the case of longer PEGylated peptidic ligands including an undecanoyl chain, the GNRs are particularly stable against aggregation for several days after purification. By controlled drying on a substrate, we showed their ability to self-organize into well-defined ordered structures making them very attractive as building blocks to design optical materials.
在此，我们描述了金纳米棒（GNRs）在其表面配体交换过程中诱导的自组装。进行了三半胱氨酸聚乙二醇化肽配体与十六烷基三甲基溴化铵（CTAB）保护的金纳米棒之间的交换反应。我们证明，肽配体的末端基团电荷（带正电或负电）和疏水性（带有或不带有十一烷酰链）强烈影响溶液中GNRs的自组装。调节短聚乙二醇化肽的量会导致溶液中金纳米棒的自组装，从而导致等离子体带发生红移或蓝移。首先通过ζ电位测定、动态光散射和紫外光谱显示了它们表面电荷的减少和在溶液中的自组装。通过小角X射线散射实验和透射电子显微镜图像，清楚地证明了纳米棒在溶液中的自组装，并将其与吸光度的光谱变化相关联。相反，对于包括十一烷酰链的较长聚乙二醇化肽配体，纯化后GNRs在几天内对聚集特别稳定。通过在基板上进行受控干燥，我们展示了它们自组装成定义明确的有序结构的能力，这使得它们作为设计光学材料的构建块非常有吸引力。
