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关于肢体肉瘤治疗后的生存情况我们了解多少?一项系统综述。

What do we know about survivorship after treatment for extremity sarcoma? A systematic review.

作者信息

Kwong T Ng Kee, Furtado S, Gerrand C

机构信息

University Hospital of North Tees, TS19 8PE, United Kingdom.

Department of Orthopaedics, Freeman Hospital, Newcastle-upon-Tyne NE7 7DN, United Kingdom.

出版信息

Eur J Surg Oncol. 2014 Sep;40(9):1109-24. doi: 10.1016/j.ejso.2014.03.015. Epub 2014 Apr 4.

DOI:10.1016/j.ejso.2014.03.015
PMID:24767804
Abstract

OBJECTIVE

The varied presentations and treatments of extremity bone and soft tissue sarcoma mean that the issues faced by survivors are diverse and complex. The aim of this systematic review was to investigate what is known about this topic with a view to identifying areas for further research or service development.

METHODS

This was a review of the English language literature identified from Medline and Ovid and hand searches published between January 2000 and September 2012. Results were compiled according to physical, psychological and social domains of survivorship.

RESULTS

Of 182 studies identified, 22 met the inclusion criteria. There is a wide range of outcome measures used and a need for more objective measures. Unsurprisingly, survivors of extremity sarcoma typically demonstrate lower levels of physical functioning than healthy controls. In addition, survivors demonstrate a substantial psychological morbidity.

CONCLUSIONS

Services for survivors of extremity sarcoma should include rehabilitation and psychological support, sexual health services, expert pain management, and support to return to work.

摘要

目的

肢体骨肉瘤和软组织肉瘤的表现及治疗方法各不相同,这意味着幸存者面临的问题多样且复杂。本系统综述的目的是调查关于该主题的已知情况,以便确定进一步研究或服务发展的领域。

方法

这是一项对2000年1月至2012年9月期间发表的、从Medline和Ovid检索到的英文文献以及手工检索文献的综述。结果根据生存的身体、心理和社会领域进行汇总。

结果

在182项被识别的研究中,22项符合纳入标准。所使用的结果测量方法种类繁多,需要更多客观的测量方法。不出所料,肢体肉瘤幸存者的身体功能水平通常低于健康对照组。此外,幸存者表现出相当程度的心理疾病。

结论

肢体肉瘤幸存者的服务应包括康复和心理支持、性健康服务、专业疼痛管理以及重返工作岗位的支持。

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