Rashidova R A, Sol'skaia L L, Godovannyĭ B A
Zh Mikrobiol Epidemiol Immunobiol. 1989 May(5):60-5.
In 157 typhoid fever patients and 36 practically healthy persons the content of neutrophils forming complement-dependent rosettes (NEAC rosette-forming cells), as well as rosettes with sheep red blood cells (NE rosette-forming cells) and with typhoid erythrocyte diagnosticum (NS rosette-forming cells), has been studied. The data obtained in this investigation indicate that antigen-binding neutrophils play an active functional role in the pathogenesis of typhoid fever at its acute stage. The values characterizing the content of N rosette-forming cells may be used as a criterion for the evaluation of the severity of infection, as well as for the prognostication of complications and relapses.
对157名伤寒热患者和36名实际健康者的形成补体依赖性玫瑰花结的中性粒细胞（NEAC玫瑰花结形成细胞）、与绵羊红细胞形成的玫瑰花结（NE玫瑰花结形成细胞）以及与伤寒红细胞诊断剂形成的玫瑰花结（NS玫瑰花结形成细胞）的含量进行了研究。本次调查获得的数据表明，在伤寒热急性期的发病机制中，抗原结合中性粒细胞发挥着积极的功能作用。表征N玫瑰花结形成细胞含量的值可用作评估感染严重程度以及预测并发症和复发的标准。
