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一种新型冠状病毒,中东呼吸综合征冠状病毒

[A novel coronavirus, MERS-CoV].

作者信息

Mizutani Tetsuya

机构信息

Research and Education Center for Prevention of Global Infectious Diseases of Animal, Tokyo University of Agriculture and Technology.

出版信息

Uirusu. 2013;63(1):1-6. doi: 10.2222/jsv.63.1.

Abstract

A novel human coronavirus was identified in Saudi Arabia and Qatar as the causative agent of severe acute respiratory diseases in 2012. The virus was termed Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and is taken notice of important coronavirus caused severe diseases to human after the outbreak of severe acute respiratory syndrome (SARS) coronavirus. There is a lot of unknown characterization regarding MERS-CoV because of less than one year after finding the first case. MERS-CoV was related to the 2C betacoronavirus clade and is closely related to Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5. Thus, bats are thought to be natural hosts of this virus. Recently, there were reports supposed to be cases of human to human infection. There are growing concerns about spread of infection.

摘要

2012年,沙特阿拉伯和卡塔尔发现了一种新型人类冠状病毒,它是严重急性呼吸道疾病的病原体。该病毒被称为中东呼吸综合征冠状病毒(MERS-CoV),是继严重急性呼吸综合征(SARS)冠状病毒爆发后引起人类严重疾病的重要冠状病毒。由于发现首例病例后不到一年,关于MERS-CoV仍有许多未知特征。MERS-CoV与2C 乙型冠状病毒进化枝相关,与伏翼蝙蝠冠状病毒HKU4和棕蝠冠状病毒HKU5密切相关。因此,蝙蝠被认为是这种病毒的天然宿主。最近,有报告称存在人际感染病例。人们对感染传播的担忧日益增加。

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