冠状病毒感染与心血管疾病关系的研究进展。
Advances in the relationship between coronavirus infection and cardiovascular diseases.
机构信息
Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China; Cardiovascular Research Institute, Wuhan University, Wuhan, China; Hubei Key Laboratory of Cardiology, Wuhan, China.
Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, 430060, China; Cardiovascular Research Institute, Wuhan University, Wuhan, China; Hubei Key Laboratory of Cardiology, Wuhan, China.
出版信息
Biomed Pharmacother. 2020 Jul;127:110230. doi: 10.1016/j.biopha.2020.110230. Epub 2020 May 13.
The outbreak of coronavirus disease 2019 (COVID-19) has once again aroused people's concern about coronavirus. Seven human coronaviruses (HCoVs) have been discovered so far, including HCoV-229E, HCoV-NL63, HCoV-OC43, HCoV-HKU115, severe acute respiratory syndrome coronavirus, Middle East respiratory syndrome coronavirus and severe acute respiratory syndrome coronavirus 2. Existing studies show that the cardiovascular disease increased the incidence and severity of coronavirus infection. At the same time, myocardial injury caused by coronavirus infection is one of the main factors contributing to poor prognosis. In this review, the recent clinical findings about the relationship between coronaviruses and cardiovascular diseases and the underlying pathophysiological mechanisms are discussed. This review aimed to provide assistance for the prevention and treatment of COVID-19.
2019 年冠状病毒病（COVID-19）的爆发再次引起了人们对冠状病毒的关注。迄今为止，已发现七种人类冠状病毒（HCoV），包括 HCoV-229E、HCoV-NL63、HCoV-OC43、HCoV-HKU115、严重急性呼吸综合征冠状病毒、中东呼吸综合征冠状病毒和严重急性呼吸综合征冠状病毒 2。现有研究表明，心血管疾病增加了冠状病毒感染的发病率和严重程度。同时，冠状病毒感染引起的心肌损伤是导致预后不良的主要因素之一。在这篇综述中，讨论了冠状病毒与心血管疾病之间的最新临床发现及其潜在的病理生理机制。本综述旨在为 COVID-19 的预防和治疗提供帮助。
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