Uçar Elalmış Ozgül, Mansuroğlu Candan, Ciçekçioğlu Hülya, Karagöz Ahmet
Department of Cardiology, Ankara Numune Training and Research Hospital, Ankara, Turkey.
Department of Cardiology, Giresun Professor Doctor Atilla İlhan Özdemir State Hospital, Giresun, Turkey.
Turk Kardiyol Dern Ars. 2014 Apr;42(3):281-4. doi: 10.5543/tkda.2014.83284.
Idiopathic hypereosinophilic syndrome (IHES) is a rare systemic disorder with blood eosinophilia and multiple system involvement. Commonly, there is endocardial fibrosis with overlying mural thrombus, and mitral and tricuspid valves can be involved concomitantly. Outflow tracts near the aortic and pulmonary valves are generally protected. We herein describe an atypical case of IHES with a mass on the left ventricular outflow tract (LVOT), which showed regression under steroid therapy. There are two features that make our case worthy of reporting: First, the mitral and tricuspid valves are expected to be involved in IHES, and outflow tracts near the aortic and pulmonary valves are generally protected. Second, within one month of steroid therapy, the vegetation had reduced dramatically in size and signs of myocarditis and pericarditis had also disappeared.
特发性嗜酸性粒细胞增多综合征（IHES）是一种罕见的全身性疾病，伴有血液嗜酸性粒细胞增多和多系统受累。通常存在心内膜纤维化并伴有附壁血栓，二尖瓣和三尖瓣可同时受累。主动脉瓣和肺动脉瓣附近的流出道一般不受影响。我们在此描述一例非典型的IHES病例，其左心室流出道（LVOT）有一个肿块，该肿块在类固醇治疗下显示消退。有两个特征使我们的病例值得报告：第一，IHES通常累及二尖瓣和三尖瓣，而主动脉瓣和肺动脉瓣附近的流出道一般不受影响。第二，在类固醇治疗的一个月内，赘生物大小显著减小，心肌炎和心包炎的体征也消失了。
