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红肉类和加工肉类在结直肠癌发展中的作用:一个视角。

The role of red and processed meat in colorectal cancer development: a perspective.

机构信息

Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, PO Box 5003, 1432 Aas, Norway.

Norwegian Institute of Public Health, PO Box 4404 Nydalen, 0403 Oslo, Norway.

出版信息

Meat Sci. 2014 Aug;97(4):583-96. doi: 10.1016/j.meatsci.2014.02.011. Epub 2014 Feb 24.

Abstract

This paper is based on a workshop held in Oslo, Norway in November 2013, in which experts discussed how to reach consensus on the healthiness of red and processed meat. Recent nutritional recommendations include reducing intake of red and processed meat to reduce cancer risk, in particular colorectal cancer (CRC). Epidemiological and mechanistic data on associations between red and processed meat intake and CRC are inconsistent and underlying mechanisms are unclear. There is a need for further studies on differences between white and red meat, between processed and whole red meat and between different types of processed meats, as potential health risks may not be the same for all products. Better biomarkers of meat intake and of cancer occurrence and updated food composition databases are required for future studies. Modifying meat composition via animal feeding and breeding, improving meat processing by alternative methods such as adding phytochemicals and improving our diets in general are strategies that need to be followed up.

摘要

本文基于 2013 年 11 月在挪威奥斯陆举行的一次研讨会,会上专家们讨论了如何就红肉类和加工肉类的健康程度达成共识。最近的营养建议包括减少红肉类和加工肉类的摄入量,以降低癌症风险,尤其是结直肠癌(CRC)。关于红肉类和加工肉类摄入量与 CRC 之间关联的流行病学和机制数据不一致,其潜在机制尚不清楚。需要进一步研究白肉和红肉之间、加工肉和整块红肉之间以及不同类型加工肉之间的差异,因为所有产品的潜在健康风险可能并不相同。未来的研究需要更好的肉类摄入量生物标志物以及癌症发生的生物标志物和更新的食物成分数据库。通过动物饲养和养殖来改变肉类成分,通过添加植物化学物质等替代方法来改进肉类加工,以及改善我们的整体饮食,这些都是需要跟进的策略。

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