来氟米特与阿达木单抗联合治疗期间出现普秃——病例报告
Alopecia universalis during treatment with leflunomide and adalimumab - case report.
作者信息
Lazzarini Rosana, Capareli Gabriela Cunha, Buense Roberta, Lellis Rute Facchini
机构信息
Santa Casa de São Paulo, São Paulo, SP, Brazil.
出版信息
An Bras Dermatol. 2014 Mar-Apr;89(2):320-2. doi: 10.1590/abd1806-4841.20142944.
Abstract
Alopecia areata is a non-scarring form of alopecia that can be localized or widespread. Its etiology is unknown, but immunological factors are implicated in its pathogenesis. With the more frequent use of anti TNFα biologic drugs, some alopecia areata cases during their use have been described. We report a case of universal alopecia in a patient with rheumatoid arthritis while using adalimumab and leflunomide.
摘要
斑秃是一种非瘢痕性脱发，可局限或广泛发生。其病因尚不清楚，但免疫因素被认为与发病机制有关。随着抗TNFα生物药物的更频繁使用，在使用过程中出现的一些斑秃病例已有报道。我们报告一例类风湿关节炎患者在使用阿达木单抗和来氟米特时发生全秃的病例。
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