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Singapore Med J. 2017 May;58(5):279-280. doi: 10.11622/smedj.2017039.
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J Cutan Med Surg. 2018 Jul/Aug;22(4):439-442. doi: 10.1177/1203475418760512. Epub 2018 Feb 20.
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Treatment of alopecia universalis with topical Janus kinase inhibitors - a double blind, placebo, and active controlled pilot study.全身性脱发采用局部 Janus 激酶抑制剂治疗：一项双盲、安慰剂和活性对照的初步研究。
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Reversal of Alopecia Universalis by Tofacitinib: A Case Report.托法替布治疗全秃症逆转：一例报告
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Topical 2% tofacitinib for children with alopecia areata, alopecia totalis, and alopecia universalis.外用2%托法替布治疗斑秃、全秃和普秃儿童。
J Am Acad Dermatol. 2018 Jun;78(6):1207-1209.e1. doi: 10.1016/j.jaad.2018.02.031.
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Successful Treatment of Refractory Alopecia Areata Universalis and Psoriatic Arthritis, But Not of Plaque Psoriasis with Tofacitinib in a Young Woman.托法替布成功治疗一名年轻女性的难治性全秃和银屑病关节炎，但对斑块状银屑病无效
Acta Derm Venereol. 2017 Feb 8;97(2):283-284. doi: 10.2340/00015555-2491.

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A Comprehensive Literature Review of JAK Inhibitors in Treatment of Alopecia Areata.JAK抑制剂治疗斑秃的综合文献综述
Clin Cosmet Investig Dermatol. 2021 Jun 25;14:691-714. doi: 10.2147/CCID.S309215. eCollection 2021.
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Scoping Review on the Use of Drugs Targeting JAK/STAT Pathway in Atopic Dermatitis, Vitiligo, and Alopecia Areata.关于靶向JAK/STAT通路药物在特应性皮炎、白癜风和斑秃中应用的范围综述
Dermatol Ther (Heidelb). 2019 Dec;9(4):655-683. doi: 10.1007/s13555-019-00329-y. Epub 2019 Oct 13.
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Role of janus kinase inhibitors in the treatment of alopecia areata.Janus激酶抑制剂在斑秃治疗中的作用。
Drug Des Devel Ther. 2018 Jul 27;12:2323-2335. doi: 10.2147/DDDT.S172638. eCollection 2018.

本文引用的文献

1
Transient Efficacy of Tofacitinib in Alopecia Areata Universalis.托法替布治疗全秃的短期疗效
Case Rep Dermatol. 2016 Apr 22;8(1):102-6. doi: 10.1159/000445182. eCollection 2016 Jan-Apr.
2
Treatment of an alopecia areata patient with tofacitinib results in regrowth of hair and changes in serum and skin biomarkers.用托法替布治疗斑秃患者可导致毛发再生以及血清和皮肤生物标志物的变化。
Exp Dermatol. 2016 Aug;25(8):642-3. doi: 10.1111/exd.13060.
3
Tofacitinib Citrate for the Treatment of Nail Dystrophy Associated With Alopecia Universalis.枸橼酸托法替布治疗全秃伴发的甲营养不良
JAMA Dermatol. 2016 Apr;152(4):492-3. doi: 10.1001/jamadermatol.2015.3772.
4
Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib.斑秃经 JAK1/2 抑制剂巴瑞替尼治疗后逆转。
EBioMedicine. 2015 Feb 26;2(4):351-5. doi: 10.1016/j.ebiom.2015.02.015. eCollection 2015 Apr.
5
Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci.斑秃的全基因组荟萃分析确定了 HLA 关联并揭示了两个新的易感基因座。
Nat Commun. 2015 Jan 22;6:5966. doi: 10.1038/ncomms6966.
6
Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition.斑秃由细胞毒性 T 淋巴细胞驱动，并可被 JAK 抑制逆转。
Nat Med. 2014 Sep;20(9):1043-9. doi: 10.1038/nm.3645. Epub 2014 Aug 17.
7
Killing two birds with one stone: oral tofacitinib reverses alopecia universalis in a patient with plaque psoriasis.一石二鸟：口服托法替布使一名斑块状银屑病患者的全秃症得到逆转。
J Invest Dermatol. 2014 Dec;134(12):2988-2990. doi: 10.1038/jid.2014.260. Epub 2014 Jun 18.
8
Alopecia universalis during treatment with leflunomide and adalimumab - case report.来氟米特与阿达木单抗联合治疗期间出现普秃——病例报告
An Bras Dermatol. 2014 Mar-Apr;89(2):320-2. doi: 10.1590/abd1806-4841.20142944.
9
Genome-wide association study in alopecia areata implicates both innate and adaptive immunity.斑秃的全基因组关联研究提示固有免疫和适应性免疫均参与其中。
Nature. 2010 Jul 1;466(7302):113-7. doi: 10.1038/nature09114.

Successful hair regrowth in a Korean patient with alopecia universalis following tofacitinib treatment.

作者信息

Kim Bo Young, Kim Hyun-Sook

机构信息

Department of Internal Medicine, Division of Rheumatology, Gangneung Asan Hospital, Gangneung, Republic of Korea.

Department of Internal Medicine, Division of Rheumatology, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.

出版信息

Singapore Med J. 2017 May;58(5):279-280. doi: 10.11622/smedj.2017039.

DOI:10.11622/smedj.2017039
PMID:28536724
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5435848/
Abstract
摘要