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牛心包补片和纤维蛋白密封剂在脊髓脊膜膨出修补术中的应用。

Use of the bovine pericardial patch and fibrin sealant in meningomyelocele closure.

作者信息

Gürer Bora, Kertmen Hayri, Akturk Umut Dogu, Kalan Mehmet, Sekerci Zeki

机构信息

Ministry of Health, Fatih Sultan Mehmet Education and Research Hospital, Neurosurgery Clinic, S.B. Fatih Sultan Mehmet Egitim ve Arastirma Hastanesi, Beyin Cerrahi Servisi, 34752, Ataşehir, Istanbul, Turkey,

出版信息

Acta Neurochir (Wien). 2014 Jul;156(7):1345-50. doi: 10.1007/s00701-014-2099-4. Epub 2014 Apr 27.

Abstract

BACKGROUND

Meningomyelocele is the most common and complex birth defect of the central nervous system. The operative principle of meningomyelocele repair consists of consecutive separate closures of the neural placode, dura mater, lumbar fascia, subcutaneous layer, and skin. While the neurosurgical techniques for the closure of the neural placode and dura mater have been well accepted, the most appropriate soft tissue closure technique has not yet been applied.

METHODS

This study reviews a case series of eight meningomyelocele patients treated with the bovine pericardial patch and fibrin sealant. Following the reconstruction of the neural placode and the closure of the dura mater, soft tissue coverage was achieved using the bovine pericardial patch and fibrin sealant.

RESULTS

In this series of eight patients, stable coverage was achieved with the application of a bovine pericardial patch and fibrin sealant technique. After the operations, none of the possible complications such as cerebrospinal fluid leak, seroma, hematoma, skin necrosis, deep or superficial infection, and wound breakdown was observed.

CONCLUSIONS

The usage of the bovine pericardial patch and fibrin sealant technique at the fascial level-between the dural sac and the skin-provides adequate soft tissue coverage in meningomyelocele repair surgery.

摘要

背景

脊髓脊膜膨出是中枢神经系统最常见且复杂的出生缺陷。脊髓脊膜膨出修复手术的操作原则包括依次分别闭合神经板、硬脑膜、腰筋膜、皮下层和皮肤。虽然闭合神经板和硬脑膜的神经外科技术已被广泛接受,但最合适的软组织闭合技术尚未得到应用。

方法

本研究回顾了一组8例接受牛心包补片和纤维蛋白密封剂治疗的脊髓脊膜膨出患者。在重建神经板并闭合硬脑膜后,使用牛心包补片和纤维蛋白密封剂实现软组织覆盖。

结果

在这组8例患者中,应用牛心包补片和纤维蛋白密封剂技术实现了稳定的覆盖。术后未观察到脑脊液漏、血清肿、血肿、皮肤坏死、深部或浅表感染以及伤口裂开等任何可能的并发症。

结论

在硬脊膜囊和皮肤之间的筋膜层面使用牛心包补片和纤维蛋白密封剂技术,在脊髓脊膜膨出修复手术中可提供足够的软组织覆盖。

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