Caciari T, Rosati M V, Sacco C, Casale T, Pimpinella B, Bonomi S, De Sio S, Giubilati R, Montuori L, Weiderpass E, Cancanelli G, Tomei G, Tomei F, Sancini A
Department of Anatomy, Histology, Medical-Legal and Orthopedics, Unit of Occupational Medicine, "Sapienza" University of Rome, Rome, Italy.
Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Clin Ter. 2014;165(2):e94-9. doi: 10.7471/CT.2014.1690.
The aim of this study was to evaluate whether urban pollutants can affect plasma levels of antidiuretic hormone (ADH) in outdoor workers.
We selected 208 subjects, 104 exposed to urban stressors and 104 non exposed to urban stressors. We divided these workers in 3 groups: Group 1 (non-smokers and non-drinkers), Group 2 (smokers and not drinkers) and Group 3 (drinkers and not smokers). The means and standard deviations of ADH were calculated, and a Student's t-test was used to compare means. The data were considered significant at p ≤ 0.05.
The outdoor workers in Group 1 had significantly reduced plasma levels of ADH. In contrast, the outdoor workers in Groups 2 and 3 had increased plasma levels of ADH. These results were consistent in both men and women.
The results suggest that urban pollutants may influence the secretion of ADH.
本研究的目的是评估城市污染物是否会影响户外工作者抗利尿激素（ADH）的血浆水平。
我们选取了208名受试者，其中104名暴露于城市应激源，104名未暴露于城市应激源。我们将这些工作者分为3组：第1组（不吸烟者且不饮酒者）、第2组（吸烟者且不饮酒者）和第3组（饮酒者且不吸烟者）。计算了ADH的均值和标准差，并使用学生t检验比较均值。数据在p≤0.05时被认为具有显著性。
第1组户外工作者的血浆ADH水平显著降低。相比之下，第2组和第3组户外工作者的血浆ADH水平升高。这些结果在男性和女性中均一致。
结果表明城市污染物可能会影响ADH的分泌。
