Groebner M, Südhoff T, Doering M, Kirmayer M, Nitsch T, Prügl L, Römer W, Wolf H, Tacke J, Massoudy P, Nüsse T, Elsner D
Klinik für Kardiologie und Pulmonologie, Klinikum Passau, Innstr. 76, 94032, Passau, Deutschland,
Internist (Berl). 2014 May;55(5):595-600. doi: 10.1007/s00108-014-3477-y.
Primary cardiac lymphoma (PCL) respresents a very rare type of cardiac tumour. This report illustrates a case of PCL in an immunocompetent 58-year-old man presenting with atrial fibrillation and febrile syndrome. Comprehensive imaging [computer tomography (CT), cardiac magnetic resonance imaging (cMRI), 3-dimensional transesophageal echocardiography (3D-TEE)] identified a large right atrial tumour, leading to pericardial effusion. Isolated cardiac involvement was confirmed by positron emission tomography (PET)-CT. A diffuse large B-cell lymphoma (DLBCL) was diagnosed based on the results of a TEE-guided biopsy. A normalized PET scan (PETAL study) indicated complete remission following R-CHOP 14 immunochemotherapy. Thus, an interdisciplinary and multimodal approach avoided unnecessary cardiac surgery.
原发性心脏淋巴瘤（PCL）是一种非常罕见的心脏肿瘤类型。本报告阐述了一例发生在免疫功能正常的58岁男性身上的PCL病例，该患者表现为心房颤动和发热综合征。综合影像学检查[计算机断层扫描（CT）、心脏磁共振成像（cMRI）、三维经食管超声心动图（3D-TEE）]发现一个巨大的右心房肿瘤，导致心包积液。正电子发射断层扫描（PET）-CT证实为孤立性心脏受累。根据经食管超声心动图（TEE）引导下活检的结果，诊断为弥漫性大B细胞淋巴瘤（DLBCL）。一次标准化的PET扫描（PETAL研究）显示在接受R-CHOP 14免疫化疗后完全缓解。因此，多学科和多模式方法避免了不必要的心脏手术。
