Norman Francesca F, López-Vélez Rogelio
Tropical Medicine Centre, Infectious Diseases Department, Ramón y Cajal Hospital, IRYCIS, Madrid 28034, Spain
Tropical Medicine Centre, Infectious Diseases Department, Ramón y Cajal Hospital, IRYCIS, Madrid 28034, Spain.
Trans R Soc Trop Med Hyg. 2014 Jul;108(7):388-90. doi: 10.1093/trstmh/tru062. Epub 2014 Apr 25.
Congenital Chagas disease may be considered a global health problem and the underdiagnosis of congenital infections should be a matter of concern. Vertical transmission is an important mode of transmission of Trypanosoma cruzi infection in non-endemic areas. Treatment in the early phases of the infection can prevent progression of the disease and is curative in the majority of cases. Prevention strategies should focus on early detection and treatment of congenital cases, screening at-risk women during pregnancy and treatment of non-pregnant women of childbearing age. Management of congenital Chagas disease and T. cruzi infection during pregnancy is discussed.
先天性恰加斯病可被视为一个全球健康问题，先天性感染的诊断不足应引起关注。垂直传播是克氏锥虫感染在非流行地区的一种重要传播方式。感染早期进行治疗可预防疾病进展，且在大多数情况下具有治愈效果。预防策略应侧重于先天性病例的早期检测与治疗、孕期对高危女性进行筛查以及对育龄非孕期女性进行治疗。本文讨论了孕期先天性恰加斯病和克氏锥虫感染的管理。
