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Fecal Microbiota Transplantation Reduces Pathology and Improves Cognition in a Mouse Model of Alzheimer's Disease.粪便微生物移植可减轻阿尔茨海默病模型小鼠的病理改变并改善认知功能。
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5xFAD mice do not have myenteric amyloidosis, dysregulation of neuromuscular transmission or gastrointestinal dysmotility.5xFAD 小鼠没有肌间神经纤维缠结、神经肌肉传递失调或胃肠动力障碍。
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本文引用的文献

1
Diet and the intestinal microbiome: associations, functions, and implications for health and disease.饮食与肠道微生物组：关联、功能以及对健康和疾病的影响。
Gastroenterology. 2014 May;146(6):1564-72. doi: 10.1053/j.gastro.2014.01.058. Epub 2014 Feb 4.
2
'The way to a man's heart is through his gut microbiota'--dietary pro- and prebiotics for the management of cardiovascular risk.“通往男人心的路是通过他的肠道微生物群”——用于管理心血管风险的饮食益生菌和益生元。
Proc Nutr Soc. 2014 May;73(2):172-85. doi: 10.1017/S0029665113003911. Epub 2014 Feb 4.
3
Effect of diet on the intestinal microbiota and its activity.饮食对肠道微生物群及其活性的影响。
Curr Opin Gastroenterol. 2014 Mar;30(2):189-95. doi: 10.1097/MOG.0000000000000048.
4
Fecal microbiota transplantation for the treatment of Clostridium difficile infection: a systematic review.粪菌移植治疗艰难梭菌感染：一项系统评价
J Clin Gastroenterol. 2014 Sep;48(8):693-702. doi: 10.1097/MCG.0000000000000046.
5
Fecal microbiota transplantation: effectiveness, complexities, and lingering concerns.粪便微生物群移植：有效性、复杂性和持续存在的问题。
Mucosal Immunol. 2014 Mar;7(2):210-4. doi: 10.1038/mi.2013.117. Epub 2014 Jan 8.
6
Role of "Western diet" in inflammatory autoimmune diseases.“西式饮食”在炎症性自身免疫性疾病中的作用。
Curr Allergy Asthma Rep. 2014 Jan;14(1):404. doi: 10.1007/s11882-013-0404-6.
7
The innate immune system in Alzheimer's disease.阿尔茨海默病中的固有免疫系统。
Int J Cell Biol. 2013;2013:576383. doi: 10.1155/2013/576383. Epub 2013 Oct 2.
8
Can a bacterial endotoxin be a key factor in the kinetics of amyloid fibril formation?细菌内毒素能否成为淀粉样纤维形成动力学的关键因素？
J Alzheimers Dis. 2014;39(1):169-79. doi: 10.3233/JAD-131394.
9
Alzheimer's disease and the microbiome.阿尔茨海默病与微生物群
Front Cell Neurosci. 2013 Sep 17;7:153. doi: 10.3389/fncel.2013.00153. eCollection 2013.
10
Current status and future promise of the human microbiome.人类微生物组的现状与未来前景
Pediatr Gastroenterol Hepatol Nutr. 2013 Jun;16(2):71-9. doi: 10.5223/pghn.2013.16.2.71. Epub 2013 Jun 30.

The gastrointestinal tract microbiome and potential link to Alzheimer's disease.

作者信息

Hill James M, Bhattacharjee Surjyadipta, Pogue Aileen I, Lukiw Walter J

机构信息

LSU Neuroscience Center, Louisiana State University Health Sciences Center , New Orleans, LA , USA ; Department of Microbiology, Louisiana State University Health Sciences Center , New Orleans, LA , USA ; Department of Ophthalmology, Louisiana State University Health Sciences Center , New Orleans, LA , USA.

LSU Neuroscience Center, Louisiana State University Health Sciences Center , New Orleans, LA , USA.

出版信息

Front Neurol. 2014 Apr 4;5:43. doi: 10.3389/fneur.2014.00043. eCollection 2014.

DOI:10.3389/fneur.2014.00043
PMID:24772103
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3983497/
Abstract
摘要