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P物质、血管活性肠肽和5-羟色胺免疫反应性结构在沙蜥中枢神经系统中的分布

Distribution of substance P, vasoactive intestinal polypeptide and serotonin immunoreactive structures in the central nervous system of the lizard, Lacerta agilis.

作者信息

Petkó M, Ihionvien M

机构信息

Department of Anatomy, University Medical School, Debrecen, Hungary.

出版信息

J Hirnforsch. 1989;30(4):415-23.

PMID:2477439
Abstract

The distribution of substance P (SP), vasoactive intestinal polypeptide (VIP) and serotonin (5-HT) containing structures in the central nervous system of the lizard, Lacerta agilis, were investigated with the aid of the peroxidase-antiperoxidase immunohistochemical method. SP and 5-HT nerve fibers are found almost all over the brain, whereas VIP fibers are mainly observed in the limbic area, in the periventricular gray matter of the diencephalon and in the brain stem. The cells of origin are located in the telencephalon for the SP, in the mesencephalic tegmentum for the VIP, and in the midline and the basis of the brain stem for the 5-HT. In addition to the known paraventricular organ in the diencephalon VIP and 5-HT immunoreactive cells are found in the ependymal layer of the rostral part of the lateral ventricle.

摘要

借助过氧化物酶-抗过氧化物酶免疫组织化学方法，对捷蜥蜴中枢神经系统中含P物质（SP）、血管活性肠多肽（VIP）和5-羟色胺（5-HT）结构的分布进行了研究。SP和5-HT神经纤维几乎遍布整个大脑，而VIP纤维主要见于边缘区、间脑的室周灰质和脑干。SP的起源细胞位于端脑，VIP的起源细胞位于中脑被盖，5-HT的起源细胞位于脑干中线和基部。除了间脑已知的室旁器官外，在侧脑室前部的室管膜层中还发现了VIP和5-HT免疫反应性细胞。

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