Qin Xiaobo, Zhang Qin, Yang Suping, Sun Zhongbo, Chen Xiaojie, Huang Huiling
Department of Electrocardiography, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
J Clin Hypertens (Greenwich). 2014 Jul;16(7):511-7. doi: 10.1111/jch.12333. Epub 2014 Apr 29.
This retrospective study aimed to investigate blood pressure variability (BPV), morning systolic blood pressure surge (MBPS), and the associated factors in 513 elderly (65 years and older) and 188 younger (younger than 65 years) hypertensive Chinese patients who had ambulatory blood pressure monitoring (ABPM) at our hospital from January 1, 2002, to December 31, 2010. The MBPS was lower in the younger patients compared with the elderly patients, and it was highest in the 75 years and older and younger than 80 group (29.0±13.4 mm Hg). Compared with other groups, the 80 years and older group had a significant increase in BPV (P<.05). Multiple linear regression analysis showed that body mass index (BMI; P<.01), up to 50 years of smoking (P≤.03), and circadian blood pressure variation (P<.01) were factors associated with MPBS. In summary, systolic BPV and MBPS were increased in elderly Chinese hypertensive patients, and the MBPS was associated with BMI, years of smoking, and circadian blood pressure variation.
这项回顾性研究旨在调查2002年1月1日至2010年12月31日期间在我院接受动态血压监测（ABPM）的513名老年（65岁及以上）和188名年轻（65岁以下）中国高血压患者的血压变异性（BPV）、晨峰收缩压（MBPS）及其相关因素。年轻患者的MBPS低于老年患者，在75岁及以上且小于80岁的组中最高（29.0±13.4 mmHg）。与其他组相比，80岁及以上组的BPV显著增加（P<0.05）。多元线性回归分析表明，体重指数（BMI；P<0.01）、吸烟达50年（P≤0.03）和昼夜血压变化（P<0.01）是与MPBS相关的因素。总之，中国老年高血压患者的收缩压BPV和MBPS升高，且MBPS与BMI、吸烟年限和昼夜血压变化有关。
