Importance of estrogen metabolites.
作者信息
Lindsey Sarah H
机构信息
From the Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA.
出版信息
Hypertension. 2014 Jul;64(1):21-2. doi: 10.1161/HYPERTENSIONAHA.114.03382. Epub 2014 Apr 28.
Abstract
摘要
相似文献
1
Importance of estrogen metabolites.雌激素代谢物的重要性。
Hypertension. 2014 Jul;64(1):21-2. doi: 10.1161/HYPERTENSIONAHA.114.03382. Epub 2014 Apr 28.
2
Estrogen metabolism by cytochrome P450 1B1 modulates the hypertensive effect of angiotensin II in female mice.细胞色素 P450 1B1 代谢雌激素调节血管紧张素 II 在雌性小鼠中的高血压效应。
Hypertension. 2014 Jul;64(1):134-40. doi: 10.1161/HYPERTENSIONAHA.114.03275. Epub 2014 Apr 28.
3
Cytochrome P450 1B1 contributes to renal dysfunction and damage caused by angiotensin II in mice.细胞色素 P450 1B1 导致血管紧张素 II 引起的小鼠肾功能障碍和损伤。
Hypertension. 2012 Feb;59(2):348-54. doi: 10.1161/HYPERTENSIONAHA.111.183301. Epub 2011 Dec 19.
4
Central CYP1B1 (Cytochrome P450 1B1)-Estradiol Metabolite 2-Methoxyestradiol Protects From Hypertension and Neuroinflammation in Female Mice.中枢细胞色素P450 1B1（CYP1B1）-雌二醇代谢物2-甲氧基雌二醇可保护雌性小鼠免受高血压和神经炎症的影响。
Hypertension. 2020 Apr;75(4):1054-1062. doi: 10.1161/HYPERTENSIONAHA.119.14548. Epub 2020 Mar 9.
5
Resveratrol prevents estrogen-DNA adduct formation and neoplastic transformation in MCF-10F cells.白藜芦醇可预防MCF - 10F细胞中雌激素 - DNA加合物的形成及肿瘤转化。
Cancer Prev Res (Phila). 2008 Jul;1(2):135-45. doi: 10.1158/1940-6207.CAPR-08-0037.
6
Specificity determinants of CYP1B1 estradiol hydroxylation.CYP1B1 雌二醇羟化的特异性决定因素。
Mol Pharmacol. 2013 Sep;84(3):451-8. doi: 10.1124/mol.113.087700. Epub 2013 Jul 2.
7
Estradiol 17β and its metabolites stimulate cell proliferation and antagonize ascorbic acid-suppressed cell proliferation in human ovarian cancer cells.雌二醇 17β及其代谢物可刺激细胞增殖，并拮抗抗坏血酸抑制人卵巢癌细胞的增殖。
Reprod Sci. 2014 Jan;21(1):102-11. doi: 10.1177/1933719113492211. Epub 2013 Jun 11.
8
CYP450- and COMT-derived estradiol metabolites inhibit activity of human coronary artery SMCs.细胞色素P450及儿茶酚-O-甲基转移酶衍生的雌二醇代谢产物可抑制人冠状动脉平滑肌细胞的活性。
Hypertension. 2003 Mar;41(3 Pt 2):807-13. doi: 10.1161/01.HYP.0000048862.28501.72. Epub 2002 Dec 23.
9
Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms.由15种选择性表达的人细胞色素P450同工型形成的17β-雌二醇和雌酮氧化代谢产物的表征。
Endocrinology. 2003 Aug;144(8):3382-98. doi: 10.1210/en.2003-0192.
10
CYP1A1 and CYP1B1 polymorphisms and their association with estradiol and estrogen metabolites in women who are premenopausal and perimenopausal.CYP1A1和CYP1B1基因多态性及其与绝经前和围绝经期女性雌二醇及雌激素代谢产物的关联。
Am J Med. 2006 Sep;119(9 Suppl 1):S44-51. doi: 10.1016/j.amjmed.2006.07.006.
引用本文的文献
1
Hypertension Management in Women With a Multidisciplinary Approach.采用多学科方法管理女性高血压
Mayo Clin Proc. 2025 Mar;100(3):514-533. doi: 10.1016/j.mayocp.2024.10.005. Epub 2024 Dec 29.
2
Identification of naturally occurring inhibitors in Xian-Ling-Gu-Bao capsule against the glucuronidation of estrogens.仙灵骨葆胶囊中天然存在的雌激素葡萄糖醛酸化抑制剂的鉴定。
Front Pharmacol. 2022 Aug 4;13:935685. doi: 10.3389/fphar.2022.935685. eCollection 2022.
3
Disruption of the cytochrome P-450 1B1 gene exacerbates renal dysfunction and damage associated with angiotensin II-induced hypertension in female mice.细胞色素P-450 1B1基因的破坏会加剧雌性小鼠中与血管紧张素II诱导的高血压相关的肾功能障碍和损伤。
Am J Physiol Renal Physiol. 2015 May 1;308(9):F981-92. doi: 10.1152/ajprenal.00597.2014. Epub 2015 Feb 18.
本文引用的文献
1
Tissue-selective estrogen complexes with bazedoxifene prevent metabolic dysfunction in female mice.贝达昔芬与雌二醇形成的组织选择性雌激素复合物可预防雌性小鼠代谢功能障碍。
Mol Metab. 2014 Jan 9;3(2):177-90. doi: 10.1016/j.molmet.2013.12.009. eCollection 2014 Apr.
2
2-methoxyestradiol binding of GPR30 down-regulates angiotensin AT(1) receptor.2-甲氧基雌二醇与 GPR30 的结合下调血管紧张素 AT(1)受体。
Eur J Pharmacol. 2014 Jan 15;723:131-40. doi: 10.1016/j.ejphar.2013.10.064. Epub 2013 Nov 18.
3
Activity of the estrogen-metabolizing enzyme cytochrome P450 1B1 influences the development of pulmonary arterial hypertension.雌激素代谢酶细胞色素 P450 1B1 的活性影响肺动脉高压的发展。
Circulation. 2012 Aug 28;126(9):1087-98. doi: 10.1161/CIRCULATIONAHA.111.062927. Epub 2012 Aug 2.
4
Sex differences in primary hypertension.原发性高血压的性别差异。
Biol Sex Differ. 2012 Mar 14;3(1):7. doi: 10.1186/2042-6410-3-7.
5
Urine biomarkers of risk in the molecular etiology of breast cancer.乳腺癌分子病因学中风险的尿液生物标志物。
Breast Cancer (Auckl). 2009 Jan 6;3:1-8. doi: 10.4137/bcbcr.s2112.
6
Reproducibility of fifteen urinary estrogens and estrogen metabolites over a 2- to 3-year period in premenopausal women.绝经前妇女十五年内尿液中雌激素和雌激素代谢产物的可重复性。
Cancer Epidemiol Biomarkers Prev. 2009 Nov;18(11):2860-8. doi: 10.1158/1055-9965.EPI-09-0591. Epub 2009 Oct 20.
7
Potential vascular actions of 2-methoxyestradiol.2-甲氧基雌二醇的潜在血管作用。
Trends Endocrinol Metab. 2009 Oct;20(8):374-9. doi: 10.1016/j.tem.2009.04.007. Epub 2009 Sep 4.
8
27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen.27-羟基胆固醇是一种内源性选择性雌激素受体调节剂，可抑制雌激素对心血管系统的作用。
Nat Med. 2007 Oct;13(10):1185-92. doi: 10.1038/nm1641. Epub 2007 Sep 16.
9
Cooxidation of steroidal and non-steroidal estrogens by purified prostaglandin synthase results in a stimulation of prostaglandin formation.纯化的前列腺素合酶对甾体和非甾体雌激素的共氧化作用会导致前列腺素生成增加。
J Steroid Biochem. 1987 Jun;26(6):679-85. doi: 10.1016/0022-4731(87)91039-9.
10
The saga of the ring B unsaturated equine estrogens.B环不饱和马雌激素的传奇故事。
Endocr Rev. 1988 Nov;9(4):396-416. doi: 10.1210/edrv-9-4-396.
Zotero 插件