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左心发育不全综合征:姑息性手术后术前人口统计学和实验室检查结果与生存率之间缺乏相关性。

Hypoplastic left heart syndrome: lack of correlation between preoperative demographic and laboratory findings and survival following palliative surgery.

作者信息

Barber G, Chin A J, Murphy J D, Pigott J D, Norwood W I

机构信息

Division of Cardiology, Children's Hospital of Philadelphia, PA 19104.

出版信息

Pediatr Cardiol. 1989 Summer;10(3):129-34. doi: 10.1007/BF02081675.

DOI:10.1007/BF02081675
PMID:2477828
Abstract

To determine whether preoperative demographic and metabolic variables correlated with early or late survival following palliative surgery for hypoplastic left heart syndrome, we reviewed the charts of 89 patients operated upon from October 1984 to January 1987. The variables analyzed were age at operation, lowest preoperative pH and H2CO3, highest preoperative arterial oxygen saturation, the occurrence of a preoperative cardiorespiratory arrest, and location of birth relative to the surgical institution. The data were evaluated by chi-squared, multivariate, and life-table analyses to the end of the first postoperative year. None of the factors analyzed significantly correlated with either short-term (less than or equal to 30 days) or long-term (greater than 30 days) survival. Thus, neither demographic nor metabolic factors including prior cardiorespiratory arrest should be considered contraindications to surgical palliation for hypoplastic left heart syndrome.

摘要

为了确定术前人口统计学和代谢变量是否与左心发育不全综合征姑息手术后的早期或晚期生存率相关,我们回顾了1984年10月至1987年1月接受手术的89例患者的病历。分析的变量包括手术年龄、术前最低pH值和H2CO3、术前最高动脉血氧饱和度、术前心肺骤停的发生情况以及出生地点与手术机构的相对位置。通过卡方分析、多变量分析和生命表分析对术后第一年年底的数据进行评估。所分析的因素均与短期(小于或等于30天)或长期(大于30天)生存率无显著相关性。因此,包括先前心肺骤停在内的人口统计学或代谢因素均不应被视为左心发育不全综合征手术姑息治疗的禁忌症。

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本文引用的文献

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Very low-birth weight infant. I. Influence of place of birth on survival.极低出生体重儿。一、出生地点对生存的影响。
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Ultrasonic recognition of aortic valve atresia in utero.子宫内主动脉瓣闭锁的超声识别
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Aortic atresia: morphologic characteristics affecting survival and operative palliation.主动脉闭锁:影响生存及手术姑息治疗的形态学特征
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Circulation. 1986 Sep;74(3 Pt 2):I70-6.