Kerner Nancy, Prudic Joan
Electroconvulsive Therapy Service & the Division of Geriatric Psychiatry, New York State Psychiatric Institute, & the College of Physicians & Surgeons of Columbia University, 1051 Riverside Drive, New York, NY 10032, USA.
Neuropsychiatry (London). 2014 Feb;4(1):33-54. doi: 10.2217/npy.14.3.
Electroconvulsive therapy (ECT) is utilized worldwide for various severe and treatment-resistant psychiatric disorders. Research studies have shown that ECT is the most effective and rapid treatment available for elderly patients with depression, bipolar disorder and psychosis. For patients who suffer from intractable catatonia and neuroleptic malignant syndrome, ECT can be life saving. For elderly patients who cannot tolerate or respond poorly to medications and who are at a high risk for drug-induced toxicity or toxic drug interactions, ECT is the safest treatment option. Organic causes are frequently associated with late-life onset of neuropsychiatric conditions, such as parkinsonism, dementia and stroke. ECT has proven to be efficacious even when these conditions are present. During the next decade, research studies should focus on the use of ECT as a synergistic therapy, to enhance other biological and psychological treatments, and prevent symptom relapse and recurrence.
电休克疗法(ECT)在全球范围内被用于治疗各种严重的、难治性精神疾病。研究表明,ECT是治疗老年抑郁症、双相情感障碍和精神病患者最有效、最快速的治疗方法。对于患有顽固性紧张症和抗精神病药物恶性综合征的患者,ECT可挽救生命。对于无法耐受药物治疗或对药物反应不佳、且有药物诱导毒性或药物相互作用高风险的老年患者,ECT是最安全的治疗选择。器质性病因常与神经精神疾病的晚年发病有关,如帕金森病、痴呆和中风。即使存在这些情况,ECT也已被证明是有效的。在未来十年,研究应聚焦于将ECT用作一种协同治疗方法,以增强其他生物和心理治疗效果,并预防症状复发。