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使用伪微焦点X射线源在诊断X射线能量下进行相衬和放大射线照相。

Phase-contrast and magnification radiography at diagnostic X-ray energies using a pseudo-microfocus X-ray source.

作者信息

Kotre C J, Robson K J

机构信息

1 Christie Medical Physics and Engineering, The Christie NHS Foundation Trust, Manchester, UK.

出版信息

Br J Radiol. 2014 Jul;87(1039):20130734. doi: 10.1259/bjr.20130734. Epub 2014 Apr 29.

Abstract

OBJECTIVE

To investigate the use of conventional diagnostic X-ray tubes for applications in which specialist microfocus sources are normally required.

METHODS

A conventional diagnostic X-ray tube was used in conjunction with a range of apertures to investigate improvements in spatial resolution using a line-pairs test object. Phase-contrast effects were investigated by varying source-to-object and object-to-receptor distances using a 2-French catheter as a clinically realistic test object.

RESULTS

For magnification radiography using a computed radiography receptor and conventional X-ray tube with a 1-mm nominal focus size, the limiting spatial resolution was improved from 3.55 line-pairs per millimetre, for a conventional contact image, to 5.6 line-pairs per millimetre, for a ×2 magnified view with a 250-µm aperture. For inline phase-contrast radiography, phase contrast enhancement of a 2-French catheter was demonstrated, and the expected trends with variations in source-to-object and object-to-receptor distances were found. Images of a neonatal phantom demonstrated a subtle improvement in visibility of a superimposed 1-French catheter simulating a percutaneously inserted central catheter for no increase in patient radiation dose.

CONCLUSION

Spatial resolution improvement and visible phase contrast can be produced in clinically relevant objects using a pseudo-microfocus geometry at X-ray energies in the normal diagnostic range, using conventional diagnostic X-ray tubes and image receptors. The disadvantages of the proposal are the large distances required to produce phase contrast and limitations imposed by the resulting tube loading.

ADVANCES IN KNOWLEDGE

It is possible to use conventional diagnostic X-ray equipment in applications that normally require microfocus X-ray sources. This presents some possibilities for clinical applications.

摘要

目的

研究常规诊断X射线管在通常需要专用微焦点源的应用中的使用情况。

方法

将常规诊断X射线管与一系列孔径配合使用,通过线对测试物体研究空间分辨率的提高。使用2法式导管作为临床实际测试物体,通过改变源到物体和物体到接收器的距离来研究相位对比效应。

结果

对于使用计算机X射线接收器和标称焦点尺寸为1毫米的常规X射线管进行的放大摄影,极限空间分辨率从常规接触图像的每毫米3.55线对提高到使用250微米孔径的×2放大视图时的每毫米5.6线对。对于在线相位对比摄影,展示了2法式导管的相位对比增强,并发现了源到物体和物体到接收器距离变化时的预期趋势。新生儿体模图像显示,模拟经皮插入中心导管的叠加1法式导管的可见度有细微改善,而患者辐射剂量没有增加。

结论

在正常诊断范围内的X射线能量下,使用常规诊断X射线管和图像接收器,采用伪微焦点几何结构,可以在临床相关物体中产生空间分辨率的提高和可见的相位对比。该提议的缺点是产生相位对比所需的距离较大以及由此产生的管负载带来的限制。

知识进展

在通常需要微焦点X射线源的应用中可以使用常规诊断X射线设备。这为临床应用带来了一些可能性。

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Quantitative methods in phase-contrast x-ray imaging.相衬X射线成像中的定量方法。
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