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本文引用的文献

1
Screening for type 2 diabetes and dysglycemia.筛查 2 型糖尿病和糖调节受损。
Epidemiol Rev. 2011;33:63-87. doi: 10.1093/epirev/mxq020. Epub 2011 May 30.
2
Diagnosis and classification of diabetes mellitus.糖尿病的诊断与分类
Diabetes Care. 2011 Jan;34 Suppl 1(Suppl 1):S62-9. doi: 10.2337/dc11-S062.
3
Update on the prevention of type 2 diabetes.2 型糖尿病预防的最新进展。
Curr Diab Rep. 2011 Feb;11(1):56-63. doi: 10.1007/s11892-010-0163-x.
4
Development and validation of a risk-score model for subjects with impaired glucose tolerance for the assessment of the risk of type 2 diabetes mellitus-The STOP-NIDDM risk-score.用于评估 2 型糖尿病风险的葡萄糖耐量受损患者风险评分模型的开发和验证——STOP-NIDDM 风险评分。
Diabetes Res Clin Pract. 2010 Feb;87(2):267-74. doi: 10.1016/j.diabres.2009.11.011. Epub 2009 Dec 22.
5
The effect of screening on the prevalence of diagnosed type 2 diabetes in primary care.筛查对初级保健中确诊的2型糖尿病患病率的影响。
Scand J Prim Health Care. 2009;27(4):232-7. doi: 10.3109/02813430903226480.
6
Effects of lifestyle changes to reduce risks of diabetes and associated cardiovascular risks: results from large scale efficacy trials.生活方式改变对降低糖尿病及相关心血管风险的影响：来自大规模疗效试验的结果。
Obesity (Silver Spring). 2009 Dec;17 Suppl 3:S43-8. doi: 10.1038/oby.2009.388.
7
10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study.糖尿病预防计划结果研究中糖尿病发病率和体重减轻的10年随访
Lancet. 2009 Nov 14;374(9702):1677-86. doi: 10.1016/S0140-6736(09)61457-4. Epub 2009 Oct 29.
8
Excess glycaemic excursions after an oral glucose tolerance test compared with a mixed meal challenge and self-measured home glucose profiles: is the OGTT a valid predictor of postprandial hyperglycaemia and vice versa?与混合餐耐量试验和自我测量的家庭血糖谱相比，口服葡萄糖耐量试验后的血糖波动过大：口服葡萄糖耐量试验是否是餐后高血糖的有效预测指标，反之亦然？
Diabetes Obes Metab. 2009 Mar;11(3):213-22. doi: 10.1111/j.1463-1326.2008.00922.x. Epub 2008 Jun 16.
9
HbA(1c) as a screening tool for detection of Type 2 diabetes: a systematic review.糖化血红蛋白（HbA(1c)）作为2型糖尿病检测的筛查工具：一项系统评价
Diabet Med. 2007 Apr;24(4):333-43. doi: 10.1111/j.1464-5491.2007.02106.x. Epub 2007 Mar 15.
10
Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis.预防或延缓糖耐量受损人群发生2型糖尿病的药物及生活方式干预：系统评价与荟萃分析
BMJ. 2007 Feb 10;334(7588):299. doi: 10.1136/bmj.39063.689375.55. Epub 2007 Jan 19.

一种用于检测高血压初级保健患者糖耐量受损的居家方法。

A home-based method for the detection of impaired glucose tolerance in hypertensive primary care patients.

作者信息

Zandén Lukas, Bergh Håkan

机构信息

Viktoriakliniken Halmstad , Sweden.

出版信息

Scand J Prim Health Care. 2014 Jun;32(2):62-6. doi: 10.3109/02813432.2014.909204. Epub 2014 Apr 29.

DOI:10.3109/02813432.2014.909204
PMID:24779455
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4075018/
Abstract

OBJECTIVE

The aim of this project was to compare an oral glucose tolerance test (OGTT) partly performed in the patient's home (OGTTh) with a clinic-obtained OGTT with regard to the ability of the tests to identify patients with impaired glucose tolerance (IGT) and type 2 diabetes mellitus (DM-2).

DESIGN

A method comparison.

SETTING

The study was completed at two primary health care centres.

SUBJECTS

Fifty-one patients with hypertension aged 50-79 years completed both OGTT tests.

MAIN OUTCOME MEASURES

Values for capillary P-glucose obtained two hours after a glucose load were compared between the two OGTT tests. Fasting plasma glucose (fP-glucose) and HbA1c were also measured.

RESULTS

Thirty-seven patients were classified in the same group (normal/IGT/DM-2) by the two tests. The index of validity based on the test's ability to identify normal or pathological values (≥ 8.9 mmol/l) was 0.75. The value for kappa was 0.66 with a sensitivity of 0.54 and a specificity of 0.82.

CONCLUSION

OGTTh may be a useful screening method for IGT in risk groups such as hypertensive patients.

摘要

目的

本项目旨在比较部分在患者家中进行的口服葡萄糖耐量试验（OGTTh）与在诊所进行的口服葡萄糖耐量试验在识别糖耐量受损（IGT）患者和2型糖尿病（DM-2）患者方面的能力。

设计

方法比较。

地点

研究在两个初级卫生保健中心完成。

受试者

51名年龄在50 - 79岁的高血压患者完成了两项口服葡萄糖耐量试验。

主要观察指标

比较两次口服葡萄糖耐量试验中葡萄糖负荷后两小时获得的毛细血管血糖值。还测量了空腹血糖（fP-葡萄糖）和糖化血红蛋白（HbA1c）。

结果

两项试验将37名患者归为同一组（正常/IGT/DM-2）。基于试验识别正常或病理值（≥8.9 mmol/l）能力的有效性指数为0.75。kappa值为0.66，敏感性为0.54，特异性为0.82。

结论

OGTTh可能是高血压等风险人群中IGT的一种有用筛查方法。