一种用于检测高血压初级保健患者糖耐量受损的居家方法。
A home-based method for the detection of impaired glucose tolerance in hypertensive primary care patients.
作者信息
Zandén Lukas, Bergh Håkan
机构信息
Viktoriakliniken Halmstad , Sweden.
出版信息
Scand J Prim Health Care. 2014 Jun;32(2):62-6. doi: 10.3109/02813432.2014.909204. Epub 2014 Apr 29.
OBJECTIVE
The aim of this project was to compare an oral glucose tolerance test (OGTT) partly performed in the patient's home (OGTTh) with a clinic-obtained OGTT with regard to the ability of the tests to identify patients with impaired glucose tolerance (IGT) and type 2 diabetes mellitus (DM-2).
DESIGN
A method comparison.
SETTING
The study was completed at two primary health care centres.
SUBJECTS
Fifty-one patients with hypertension aged 50-79 years completed both OGTT tests.
MAIN OUTCOME MEASURES
Values for capillary P-glucose obtained two hours after a glucose load were compared between the two OGTT tests. Fasting plasma glucose (fP-glucose) and HbA1c were also measured.
RESULTS
Thirty-seven patients were classified in the same group (normal/IGT/DM-2) by the two tests. The index of validity based on the test's ability to identify normal or pathological values (≥ 8.9 mmol/l) was 0.75. The value for kappa was 0.66 with a sensitivity of 0.54 and a specificity of 0.82.
CONCLUSION
OGTTh may be a useful screening method for IGT in risk groups such as hypertensive patients.
目的
本项目旨在比较部分在患者家中进行的口服葡萄糖耐量试验（OGTTh）与在诊所进行的口服葡萄糖耐量试验在识别糖耐量受损（IGT）患者和2型糖尿病（DM-2）患者方面的能力。
设计
方法比较。
地点
研究在两个初级卫生保健中心完成。
受试者
51名年龄在50 - 79岁的高血压患者完成了两项口服葡萄糖耐量试验。
主要观察指标
比较两次口服葡萄糖耐量试验中葡萄糖负荷后两小时获得的毛细血管血糖值。还测量了空腹血糖（fP-葡萄糖）和糖化血红蛋白（HbA1c）。
结果
两项试验将37名患者归为同一组（正常/IGT/DM-2）。基于试验识别正常或病理值（≥8.9 mmol/l）能力的有效性指数为0.75。kappa值为0.66，敏感性为0.54，特异性为0.82。
结论
OGTTh可能是高血压等风险人群中IGT的一种有用筛查方法。
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