Harada Y, Yamaha M, Saito A, Takeuchi T, Kanematsu M, Kuriyama M, Ban Y, Kawada Y, Tanaka T, Shimokawa K
Department of Urology, Gifu University School of Medicine.
Hinyokika Kiyo. 1989 Jun;35(6):1009-14.
A 37-year-old male was presented with an upper abdominal mass. A retroperitoneal bulky tumor was detected and operative biopsy revealed seminoma. The right testis was undescended and atrophic which was located at the left inguinal lesion. Pathologically, the primary tumor cells were not found in the left orchiectomied testis, but only scar and fibrosis were compatible with a burned-out testicular tumor. This patient showed partial regression by multidisciplinary therapy including combined chemotherapy with CDDP, etoposide and peplomycin, and is still on the same condition and alive for 3 years. In case of extragonadal germ cell tumor without apparent testicular involvement, it is a problem to differentiate primary extragonadal germ cell tumor from occult and burned-out testicular tumor. Testis should be examined by all means available including careful exploration.
一名37岁男性因上腹部肿块就诊。检查发现腹膜后有一巨大肿瘤，手术活检显示为精原细胞瘤。右侧睾丸未降且萎缩，位于左侧腹股沟病变处。病理检查显示，左侧睾丸切除标本中未发现原发性肿瘤细胞，仅见瘢痕和纤维化，符合已消退的睾丸肿瘤表现。该患者接受了包括顺铂、依托泊苷和培普利霉素联合化疗在内的多学科治疗，部分肿瘤有所消退，目前病情稳定，已存活3年。对于无明显睾丸受累的性腺外生殖细胞肿瘤，鉴别原发性性腺外生殖细胞肿瘤与隐匿性及已消退的睾丸肿瘤是一个难题。应采用一切可用方法检查睾丸，包括仔细探查。
