Berthold P, Brönnimann M, Wegmüller E
Medizinische Klinik Regionalspital Interlaken, Universität Bern.
Praxis (Bern 1994). 2000 Feb 10;89(7):291-6.
A 44-year old male presented himself with left-sided abdominal pain. On clinical examination a painless, enlarged supraclavicular lymph node on the left side and small atrophic testes were detected. Ultrasonography revealed a huge retroperitoneal mass. By biopsy of the retroperitoneal tumor the diagnosis of a seminoma was made, but neither in the orchidectomy specimen of the right side nor in the testicular biopsy of the left side a primary tumor or a scar could be identified. Thus, the diagnosis of a extragonadal primary retroperitoneal seminoma was made. The patient responded well to the combined chemotherapy consisting of cisplatin, bleomycin and etoposide. For distinction from an occult and/or burned-out seminoma testicular biopsy or surgical exploration of the testes with histology are mandatory.
一名44岁男性因左侧腹痛就诊。临床检查发现左侧有无痛性、肿大的锁骨上淋巴结及小的萎缩性睾丸。超声检查显示腹膜后有巨大肿块。通过腹膜后肿瘤活检诊断为精原细胞瘤,但右侧睾丸切除标本及左侧睾丸活检均未发现原发肿瘤或瘢痕。因此,诊断为性腺外原发性腹膜后精原细胞瘤。该患者对顺铂、博来霉素和依托泊苷联合化疗反应良好。为了与隐匿性和/或消退型精原细胞瘤相鉴别,睾丸活检或睾丸手术探查及组织学检查是必需的。