Lu Young, Qureshi Sheeraz A
Department of Orthopaedic Surgery, Mount Sinai Medical Center, 5 E. 98 St, 9th Floor, Box 1188, New York, NY 10029, USA.
Department of Orthopaedic Surgery, Mount Sinai Medical Center, 5 E. 98 St, 9th Floor, Box 1188, New York, NY 10029, USA.
Spine J. 2014 Nov 1;14(11):2748-62. doi: 10.1016/j.spinee.2014.04.026. Epub 2014 Apr 26.
Although the pathologic processes that affect the spine remain largely unchanged, our techniques to correct them continue to evolve with the development of novel medical and surgical interventions. Although the primary purpose of new technologies is to improve patients' quality of life, the economic impact of such therapies must be considered.
To review the available peer-reviewed literature on spine surgery that addresses the cost-effectiveness of various treatments and technologies.
A narrative literature review.
Articles published between January 1, 2000 and December 31, 2012 were selected from two Pubmed searches using keywords cost-effectiveness AND spine (216 articles) and cost analysis AND spine (358 articles). Relevant articles on cost analyses and cost-effectiveness were selected by the authors and reviewed.
Cervical and lumbar surgeries (anterior cervical discectomy and fusion, standard open lumbar discectomy, and standard posterior lumbar laminectomy) are reasonably cost effective at 2 years after the procedure (<100,000 US dollars per quality-adjusted life years gained) and become more cost effective with time because of sustained clinical improvements with relatively low additional incurred costs. The usage of transfusion avoidance technology is not cost effective because of the low risk of complications associated with allogenic transfusions. Although intraoperative neuromonitoring and imaging modalities are both cost saving and cost-effective, their cost-effectiveness is largely dependent on the baseline rate of neurologic complications and implant misplacement, respectively. More rigorous studies are needed to evaluate the cost-effectiveness of recombinant bone morphogenetic protein.
An ideal new technology should be able to achieve maximal improvement in patient health at a cost that society is willing to pay. The cost-effectiveness of technologies and treatments in spine care is dependent on their durability and the rate and severity of the baseline clinical problem that the treatment was designed to address.
尽管影响脊柱的病理过程在很大程度上保持不变,但随着新型医学和外科干预措施的发展,我们矫正这些病理过程的技术仍在不断演变。虽然新技术的主要目的是提高患者的生活质量,但必须考虑此类治疗的经济影响。
回顾关于脊柱手术的同行评审文献,这些文献涉及各种治疗方法和技术的成本效益。
叙述性文献综述。
从两个PubMed搜索中选择2000年1月1日至2012年12月31日发表的文章,搜索关键词为“成本效益”和“脊柱”(216篇文章)以及“成本分析”和“脊柱”(358篇文章)。作者选择并评审了有关成本分析和成本效益的相关文章。
颈椎和腰椎手术(前路颈椎间盘切除融合术、标准开放式腰椎间盘切除术和标准后路腰椎椎板切除术)在术后2年时具有合理的成本效益(每获得一个质量调整生命年的成本<100,000美元),并且随着时间的推移成本效益更高,因为持续的临床改善伴随着相对较低的额外成本。由于异体输血相关并发症风险较低,避免输血技术不具有成本效益。虽然术中神经监测和成像方式既节省成本又具有成本效益,但它们的成本效益分别在很大程度上取决于神经并发症和植入物误置的基线发生率。需要更严格的研究来评估重组骨形态发生蛋白的成本效益。
一项理想的新技术应该能够以社会愿意支付的成本实现患者健康的最大改善。脊柱护理中技术和治疗方法的成本效益取决于它们的持久性以及该治疗旨在解决的基线临床问题的发生率和严重程度。