Smith J, Douglas J, Smith B, Dougherty T, Ayshford C
Worcestershire Acute Hospital NHS Trust, UK.
Ann R Coll Surg Engl. 2014 Mar;96(2):130-5. doi: 10.1308/003588414X13814021676594.
There is disparity in the reported incidence of temporary and permanent recurrent laryngeal nerve (RLN) palsy following thyroidectomy. Much of the disparity is due to the method of assessing vocal cord function. We sought to identify the incidence and natural history of temporary and permanent vocal cord palsy following thyroid surgery. The authors wanted to establish whether intraoperative nerve monitoring and stimulation aids in prognosis when managing vocal cord palsy.
Prospective data on consecutive thyroid operations were collected. Intraoperative nerve monitoring and stimulation, using an endotracheal tube mounted device, was performed in all cases. Endoscopic examination of the larynx was performed on the first postoperative day and at three weeks.
Data on 102 patients and 123 nerves were collated. Temporary and permanent RLN palsy rates were 6.1% and 1.7%. Most RLN palsies were identified on the first postoperative day with all recognised at the three-week review. No preoperative clinical risk factors were identified. Although dysphonia at the three-week follow-up visit was the only significant predictor of vocal cord palsy, only two-thirds of patients with cord palsies were dysphonic. Intraoperative nerve monitoring and stimulation did not predict outcome in terms of vocal cord function.
Temporary nerve palsy rates were consistent with other series where direct laryngoscopy is used to assess laryngeal function. Direct laryngoscopy is the only reliable measure of cord function, with intraoperative monitoring being neither a reliable predictor of cord function nor a predictor of eventual laryngeal function. The fact that all temporary palsies recovered within four months has implications for staged procedures.
甲状腺切除术后暂时性和永久性喉返神经(RLN)麻痹的报告发病率存在差异。这种差异很大程度上归因于声带功能的评估方法。我们试图确定甲状腺手术后暂时性和永久性声带麻痹的发病率及自然病程。作者想要确定术中神经监测和刺激在处理声带麻痹时是否有助于判断预后。
收集连续甲状腺手术的前瞻性数据。所有病例均使用安装在气管导管上的装置进行术中神经监测和刺激。术后第一天和三周时进行喉镜内镜检查。
整理了102例患者和123条神经的数据。暂时性和永久性喉返神经麻痹发生率分别为6.1%和1.7%。大多数喉返神经麻痹在术后第一天被发现,所有病例在三周复查时均被识别。未发现术前临床危险因素。虽然三周随访时的发音障碍是声带麻痹的唯一显著预测因素,但只有三分之二的声带麻痹患者存在发音障碍。术中神经监测和刺激在声带功能方面无法预测结果。
暂时性神经麻痹发生率与其他使用直接喉镜评估喉功能的系列研究一致。直接喉镜检查是评估声带功能的唯一可靠方法,术中监测既不是声带功能的可靠预测指标,也不是最终喉功能的预测指标。所有暂时性麻痹在四个月内恢复这一事实对分期手术有影响。