Lillis D L, Hanson P
Cardiology Section, University of Wisconsin, Clinical Science Center, Madison.
Clin Cardiol. 1989 Oct;12(10):569-74. doi: 10.1002/clc.4960121004.
We evaluated the effect of routine exercise training sessions on the frequency of ventricular ectopic activity (VEA) in 18 coronary artery disease patients (mean age = 60 years) who were active participants in a cardiac rehabilitation program. Nine patients were classified as high risk and nine patients were low risk according to clinical status and cardiac catheterization criteria. Five patients in each group were on beta blockade, but none were on antiarrhythmic agents. Serial 24-h ECG monitoring was obtained on a routine supervised exercise day and nonexercise control day. VEA were compared during three time periods: (1) exercise training and recovery (4 h) and the corresponding 4 h during control, (2) activities of daily living (12 h), and (3) sleep (8 h). Both groups showed a moderate increase in total VEA during the three activity periods from control day to exercise day. However, this increase was only significant (p less than 0.05) in the high-risk group during the 12-h activity of daily living period postexercise. VEA was significantly greater (p less than 0.05) in the high-risk group during all activity intervals except the sleep period on the exercise day. We conclude that VEA occurs with similar frequency during exercise training or corresponding control periods. High-risk patients have significantly greater VEA on exercise and control days and show additional increased in VEA during activities of daily living (eating and driving) on exercise days.
我们评估了常规运动训练课程对18名冠状动脉疾病患者（平均年龄 = 60岁）室性异位活动（VEA）频率的影响，这些患者是心脏康复计划的积极参与者。根据临床状况和心导管检查标准，9名患者被归类为高危患者，9名患者为低危患者。每组中有5名患者正在接受β受体阻滞剂治疗，但均未服用抗心律失常药物。在常规监督运动日和非运动对照日进行连续24小时心电图监测。在三个时间段比较VEA：（1）运动训练和恢复阶段（4小时）以及对照阶段相应的4小时，（2）日常生活活动阶段（12小时），以及（3）睡眠阶段（8小时）。从对照日到运动日，两组在三个活动阶段的总VEA均有适度增加。然而，这种增加仅在高危组运动后12小时日常生活活动阶段有统计学意义（p<0.05）。在运动日，除睡眠阶段外，高危组在所有活动间隔的VEA均显著更高（p<0.05）。我们得出结论，运动训练期间或相应对照阶段VEA出现的频率相似。高危患者在运动日和对照日的VEA显著更高，并且在运动日的日常生活活动（进食和驾驶）期间VEA进一步增加。
