• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[mts271克隆的DNA序列在各种肿瘤和正常小鼠细胞中转录的研究]

[Study of transcription of the DNA sequence of a mts271 clone in various tumor and normal mouse cells].

作者信息

Grigorian M S, Ebralidze A K, Tyl'chinskiĭ E M, Revazova E S, Senin V M, Lukanidin E M

出版信息

Genetika. 1989 Jun;25(6):993-1000.

PMID:2478418
Abstract

Transcription of the mts271 gene was studied in 27 mouse cell tumor lines. Transcripts of the gene have been found in 6 out of 7 different metastatic lines. No transcription of the gene has been observed in non-metastatic tumor lines. In normal tissues, specific gene DNA was only found in hemopoietic cells--in bone marrow, spleen, thymus and lymphocytes. Transcription of the gene mts271 is not dependent on the level of DNA methylation.

摘要

在27种小鼠细胞肿瘤系中研究了mts271基因的转录情况。在7种不同的转移系中有6种发现了该基因的转录本。在非转移肿瘤系中未观察到该基因的转录。在正常组织中,仅在造血细胞——骨髓、脾脏、胸腺和淋巴细胞中发现了特定的基因DNA。mts271基因的转录不依赖于DNA甲基化水平。

相似文献

1
[Study of transcription of the DNA sequence of a mts271 clone in various tumor and normal mouse cells].[mts271克隆的DNA序列在各种肿瘤和正常小鼠细胞中转录的研究]
Genetika. 1989 Jun;25(6):993-1000.
2
[Isolation of cDNA clones which are specifically transcribed in metastatic and nonmetastatic murine tumors].[在转移性和非转移性小鼠肿瘤中特异性转录的cDNA克隆的分离]
Genetika. 1989 May;25(5):932-6.
3
Transcription of a novel mouse semaphorin gene, M-semaH, correlates with the metastatic ability of mouse tumor cell lines.
Cancer Res. 1998 Mar 15;58(6):1238-44.
4
Invasive and metastatic potential induced by ras-transfection into mouse BW5147 T-lymphoma cells.将ras基因转染至小鼠BW5147 T淋巴瘤细胞中所诱导的侵袭和转移潜能。
Cancer Res. 1987 Feb 1;47(3):754-9.
5
Transcripts of the mitochondrial gene ND5 are overexpressed in highly metastatic murine large cell lymphoma cells.线粒体基因ND5的转录本在高转移性小鼠大细胞淋巴瘤细胞中过表达。
In Vivo. 1992 Jul-Aug;6(4):317-24.
6
Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing.正常及转化的人类组织中,p16/CDKN2肿瘤抑制基因5' CpG岛的甲基化与基因沉默相关。
Cancer Res. 1995 Oct 15;55(20):4531-5.
7
[Enhanced transcription of genes of the intracisternal A particles and B2 elements in mouse tumors].
Mol Biol (Mosk). 1985 Mar-Apr;19(2):340-8.
8
Androgen deprivation induces selective outgrowth of aggressive hormone-refractory prostate cancer clones expressing distinct cellular and molecular properties not present in parental androgen-dependent cancer cells.雄激素剥夺诱导侵袭性激素难治性前列腺癌克隆的选择性生长,这些克隆表达亲代雄激素依赖性癌细胞中不存在的独特细胞和分子特性。
Cancer J. 2000 Jul-Aug;6(4):220-33.
9
The identification of osteopontin as a metastasis-related gene product in a rodent mammary tumour model.在啮齿动物乳腺肿瘤模型中骨桥蛋白作为转移相关基因产物的鉴定。
Oncogene. 1996 Jul 4;13(1):97-104.
10
Correlation of undermethylation of intracisternal A-particle genes with expression in murine plasmacytomas but not in NIH/3T3 embryo fibroblasts.脑池内A颗粒基因低甲基化与小鼠浆细胞瘤而非NIH/3T3胚胎成纤维细胞中表达的相关性。
Cancer Res. 1984 Nov;44(11):5234-41.