Grigorian M S, Ebralidze A K, Tyl'chinskiĭ E M, Revazova E S, Senin V M, Lukanidin E M
Genetika. 1989 Jun;25(6):993-1000.
Transcription of the mts271 gene was studied in 27 mouse cell tumor lines. Transcripts of the gene have been found in 6 out of 7 different metastatic lines. No transcription of the gene has been observed in non-metastatic tumor lines. In normal tissues, specific gene DNA was only found in hemopoietic cells--in bone marrow, spleen, thymus and lymphocytes. Transcription of the gene mts271 is not dependent on the level of DNA methylation.
在27种小鼠细胞肿瘤系中研究了mts271基因的转录情况。在7种不同的转移系中有6种发现了该基因的转录本。在非转移肿瘤系中未观察到该基因的转录。在正常组织中,仅在造血细胞——骨髓、脾脏、胸腺和淋巴细胞中发现了特定的基因DNA。mts271基因的转录不依赖于DNA甲基化水平。