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[在转移性和非转移性小鼠肿瘤中特异性转录的cDNA克隆的分离]

[Isolation of cDNA clones which are specifically transcribed in metastatic and nonmetastatic murine tumors].

作者信息

Ebralidze A K, Tul'chinskiĭ E M, Grigorian M S, Senin V M, Lukanidin E M

出版信息

Genetika. 1989 May;25(5):932-6.

PMID:2744442
Abstract

Gene cloning was used with a view to examine differences in gene expression in metastatic (CSML-100) and non-metastatic (CSML-0) cell lines. Differential screening of the cDNA libraries obtained was performed. Mts271 gene which is specifically expressed in metastatic cells was isolated.

摘要

为了研究转移性(CSML-100)和非转移性(CSML-0)细胞系中基因表达的差异,采用了基因克隆技术。对所获得的cDNA文库进行了差异筛选。分离出了在转移性细胞中特异性表达的Mts271基因。

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