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2013 年,中东呼吸综合征冠状病毒(MERS-CoV)在阿曼的单峰驼中出现。

Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels, Oman, 2013.

机构信息

Viral Zoonoses, Emerging and Vector-Borne Infections Group, Institute of Virology, University of Veterinary Medicine Vienna, Vienna, Austria.

出版信息

Euro Surveill. 2014 Apr 24;19(16):20781. doi: 10.2807/1560-7917.es2014.19.16.20781.

Abstract

A countrywide survey in Oman revealed Middle Eastrespiratory syndrome coronavirus (MERS-CoV) nucleicacid in five of 76 dromedary camels. Camel-derivedMERS-CoV sequences (3,754 nucleotides assembled from partial sequences of the open reading frame (ORF)1a, spike, and ORF4b genes) from Oman and Qatar were slightly different from each other, but closely related to human MERS-CoV sequences from the same geographical areas, suggesting local zoonotic transmission. High viral loads in nasal and conjunctival swabs suggest possible transmission by the respiratory route.

摘要

一项在阿曼开展的全国性调查显示,在 76 只单峰驼中,有 5 只检测出中东呼吸综合征冠状病毒(MERS-CoV)核酸。从阿曼和卡塔尔分离出的骆驼源性 MERS-CoV 序列(从开放阅读框 1a、刺突和 ORF4b 基因的部分序列组装得到的 3754 个核苷酸)彼此略有不同,但与同一地理区域的人源 MERS-CoV 序列密切相关,提示存在局部人畜共传现象。鼻拭子和结膜拭子中的高病毒载量提示可能通过呼吸道传播。

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