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贫血对死亡率的短期影响:来自墨西哥老年人样本的证据。

Short-Term Impact of Anemia on Mortality: Evidence From a Sample of Mexican Older Adults.

作者信息

De la Cruz-Góngora Vanessa, Manrique-Espinoza Betty, Villalpando Salvador, Téllez-Rojo Solís Martha María, Salinas-Rodriguez Aarón

机构信息

National Institute of Public Health, Cuernavaca, Mexico.

National Institute of Public Health, Cuernavaca, Mexico

出版信息

J Aging Health. 2014 Aug;26(5):750-765. doi: 10.1177/0898264314529331. Epub 2014 Apr 30.

DOI:10.1177/0898264314529331
PMID:24788718
Abstract

OBJECTIVE

To estimate the short-term (14 months) impact of anemia on mortality among Mexican older adults (OAs).

METHOD

Longitudinal analyses using data from a quasi-experimental study in a non-contributory pension program in Mexico with a sample of 3,621 OAs aged 65 to 74 years. Data on health, nutrition, life conditions, and mortality were gathered at both baseline and follow-up. Logistic regression model was used to estimate the impact of anemia and hemoglobin quintiles on mortality.

RESULTS

Overall mortality rate was 2.1%. Both mild anemia and moderate/severe anemia increased mortality risk at 14 months (odds ratio [OR] = 2.04, 95% confidence interval [CI] = [1.1, 4.1]; and OR = 6, 95% CI = [2.1, 16.9], respectively).

DISCUSSION

In the short term, degree of severity of anemia is an independent predictor of mortality risk. Because anemia is a modifiable factor, further research is required to better understand this condition in terms of main causes, prevention, treatment, and impact on OAs' survival.

摘要

目的

评估贫血对墨西哥老年人(OA)死亡率的短期(14个月)影响。

方法

采用墨西哥一项非缴费型养老金计划的准实验研究数据进行纵向分析,样本为3621名年龄在65至74岁的老年人。在基线和随访时收集健康、营养、生活状况和死亡率数据。使用逻辑回归模型评估贫血和血红蛋白五分位数对死亡率的影响。

结果

总死亡率为2.1%。轻度贫血和中度/重度贫血均增加了14个月时的死亡风险(优势比[OR]=2.04,95%置信区间[CI]=[1.1,4.1];OR=6,95%CI=[2.1,16.9])。

讨论

短期内,贫血的严重程度是死亡风险的独立预测因素。由于贫血是一个可改变的因素,需要进一步研究以更好地了解这种情况的主要原因、预防、治疗以及对老年人生存的影响。

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