ADAMTS13, TTP and Beyond.
作者信息
Zheng X Long
机构信息
Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia and The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19194, USA.
出版信息
Hereditary Genet. 2013;2(1):e104. doi: 10.4172/2161-1041.1000e104.
Abstract
摘要
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本文引用的文献
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Antigen and substrate withdrawal in the management of autoimmune thrombotic disorders.抗原和底物去除在自身免疫性血栓性疾病治疗中的应用。
Blood. 2012 Nov 15;120(20):4134-42. doi: 10.1182/blood-2012-06-389445. Epub 2012 Sep 10.
2
Protective anti-inflammatory effect of ADAMTS13 on myocardial ischemia/reperfusion injury in mice.ADAMTS13 对小鼠心肌缺血/再灌注损伤的保护抗炎作用。
Blood. 2012 Dec 20;120(26):5217-23. doi: 10.1182/blood-2012-06-439935. Epub 2012 Aug 22.
3
Genetic ablation of Adamts13 gene dramatically accelerates the formation of early atherosclerosis in a murine model.基因敲除 Adamts13 基因可显著加速小鼠模型早期动脉粥样硬化的形成。
Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):1817-23. doi: 10.1161/ATVBAHA.112.247262. Epub 2012 May 31.
4
Unexpected frequency of Upshaw-Schulman syndrome in pregnancy-onset thrombotic thrombocytopenic purpura.妊娠相关性血栓性血小板减少性紫癜中 Upshaw-Schulman 综合征的意外高频率。
Blood. 2012 Jun 14;119(24):5888-97. doi: 10.1182/blood-2012-02-408914. Epub 2012 Apr 30.
5
Gain-of-function ADAMTS13 variants that are resistant to autoantibodies against ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura.获得功能的 ADAMTS13 变异体，对获得性血栓性血小板减少性紫癜患者针对 ADAMTS13 的自身抗体具有抗性。
Blood. 2012 Apr 19;119(16):3836-43. doi: 10.1182/blood-2011-12-399501. Epub 2012 Jan 30.
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Association of ADAMTS13 polymorphism with cerebral malaria.ADAMTS13 多态性与脑型疟疾的关联。
Malar J. 2011 Dec 14;10:366. doi: 10.1186/1475-2875-10-366.
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ADAMTS13 reduces vascular inflammation and the development of early atherosclerosis in mice.ADAMTS13 可减少小鼠血管炎症和早期动脉粥样硬化的发生。
Blood. 2012 Mar 8;119(10):2385-91. doi: 10.1182/blood-2011-09-376202. Epub 2011 Nov 28.
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High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women.高 VWF、低 ADAMTS13 和口服避孕药会增加年轻女性发生缺血性卒中和心肌梗死的风险。
Blood. 2012 Feb 9;119(6):1555-60. doi: 10.1182/blood-2011-09-380618. Epub 2011 Nov 22.
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Essential domains of a disintegrin and metalloprotease with thrombospondin type 1 repeats-13 metalloprotease required for modulation of arterial thrombosis.对于动脉血栓形成的调节所必需的整合素和金属蛋白酶与血小板反应蛋白-1 型重复 13 金属蛋白酶的必需结构域。
Arterioscler Thromb Vasc Biol. 2011 Oct;31(10):2261-9. doi: 10.1161/ATVBAHA.111.229609. Epub 2011 Jul 28.
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Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain.残基 Arg568 和 Phe592 有助于在间隔区中针对 ADAMTS13 抗体的抗原表面。
Haematologica. 2011 Nov;96(11):1670-7. doi: 10.3324/haematol.2010.036327. Epub 2011 Jun 28.
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