Angelova P, Davidoff M
Z Mikrosk Anat Forsch. 1989;103(4):560-6.
The cellular localization of substance P immunoreactivity was demonstrated at the light microscopical level in the hamster testis during fetal and postnatal development. A selective immunostaining was observed both of fetal and adult generation of Leydig cells. The comparison of the immunocytochemical findings with the ultrastructural characteristics of Leydig cells provided evidence that Leydig cells besides their androgen-producing capacity also had an neuropeptide producing function. The possible role of substance P in the local paracrine control of gametogenesis was discussed.
在胎儿和出生后发育阶段的仓鼠睾丸中，通过光学显微镜观察到了P物质免疫反应性的细胞定位。在胎儿和成年期的睾丸间质细胞中均观察到选择性免疫染色。将免疫细胞化学结果与睾丸间质细胞的超微结构特征进行比较，结果表明，睾丸间质细胞除了具有产生雄激素的能力外，还具有产生神经肽的功能。文中还讨论了P物质在配子发生的局部旁分泌调控中的可能作用。
