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2003年至2011年上海杨浦区阻塞性肺疾病死亡情况:多病因分析

Deaths of obstructive lung disease in the Yangpu district of Shanghai from 2003 through 2011: a multiple cause analysis.

作者信息

Cheng Yi, Han Xue, Luo Yong, Xu Weiguo

机构信息

Department of Respiratory Medicine, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.

Shanghai Yangpu District Center for Disease Control and Prevention, Shanghai 200090, China.

出版信息

Chin Med J (Engl). 2014;127(9):1619-25.

Abstract

BACKGROUND

Obstructive lung disease (OLD, chronic obstructive pulmonary disease or asthma) is an important cause of death in older people. There has been no exhaustive population-based mortality study of this subject in Shanghai. The objective of this study was to use a multiple cause of death methodology in the analysis of OLD mortality trends in the Yangpu district of Shanghai, from 2003 through 2011.

METHODS

We analyzed death data from the Shanghai Yangpu District Center for Disease Control and Prevention for Medical Cause of Death database, selecting all death certificates for individuals 40 years or older on which OLD was listed as a cause of death.

RESULTS

From 2003 to 2011, there were 8 775 deaths with OLD listed, of which 6 005 (68%) were identified as the underlying cause of death. For the entire period, a significantly decreasing trend of age standardized rates of death from OLD was observed in men (-6.2% per year) and in women (-5.7% per year), similar trends were observed in deaths with OLD. The mean annual rates of deaths from OLD per 100 000 were 161.2 for men and 80.8 for women from 2003 to 2011. While, as the underlying cause of death, the main associated causes of death were as follows: cardiovascular diseases (70.7%), cerebrovascular diseases (13.3%), diabetes (8.6%), and cancer (4.3%). The associated causes and the principal overall underlying causes of death were cardiovascular diseases (37.0%), cancer (30.3%), and cerebrovascular disease (15.3%). A significant seasonal variation, with the highest frequency in winter, occurred in deaths identified with underlying causes of chronic bronchitis, other obstructive pulmonary diseases, and asthma.

CONCLUSIONS

Multiple cause mortality analysis provides a more accurate picture than underlying cause of total mortality attributed on death certificates to OLD. The major comorbidities associated with OLD were cardiovascular disease, cancer, and cerebrovascular disease. From 2003 to 2011, the mortality rate from OLD decreased substantially in the Yangpu district of Shanghai.

摘要

背景

阻塞性肺病(OLD,慢性阻塞性肺疾病或哮喘)是老年人死亡的重要原因。上海尚未有基于人群的关于该主题的详尽死亡率研究。本研究的目的是运用多死因分析方法,分析2003年至2011年上海杨浦区OLD的死亡率趋势。

方法

我们分析了上海市杨浦区疾病预防控制中心死因数据库中的死亡数据,选取了所有40岁及以上且将OLD列为死因的死亡证明。

结果

2003年至2011年,有8775例死亡病例被列为OLD,其中6005例(68%)被确定为根本死因。在整个研究期间,男性OLD年龄标准化死亡率呈显著下降趋势(每年-6.2%),女性也呈下降趋势(每年-5.7%),OLD相关死亡也呈现类似趋势。2003年至2011年,男性每10万人口中OLD的年平均死亡率为161.2,女性为80.8。作为根本死因,主要相关死因如下:心血管疾病(70.7%)、脑血管疾病(13.3%)、糖尿病(8.6%)和癌症(4.3%)。相关死因及主要总体根本死因依次为心血管疾病(37.0%)、癌症(30.3%)和脑血管疾病(15.3%)。慢性支气管炎、其他阻塞性肺病和哮喘作为根本死因的死亡存在显著的季节性变化,冬季出现频率最高。

结论

多死因死亡率分析比死亡证明上归因于OLD的根本死因能更准确地反映总死亡率情况。与OLD相关的主要合并症为心血管疾病、癌症和脑血管疾病。2003年至2011年,上海杨浦区OLD死亡率大幅下降。

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