Mannino D M, Brown C, Giovino G A
Air Pollution and Respiratory Health Branch, National Center for Environmental Health (NCEH), Atlanta, Georgia, USA.
Am J Respir Crit Care Med. 1997 Sep;156(3 Pt 1):814-8. doi: 10.1164/ajrccm.156.3.9702026.
We analyzed mortality trends among people who died with a diagnosis of obstructive lung disease from 1979 through 1993, using death certificate reports of 31,314,160 decedents in the Multiple-Cause Mortality Files compiled by the National Center for Health Statistics. Of all the decedents, 2,554,959 (8.2%) had a diagnosis of obstructive lung disease (ICD-9 490 to 493.9, 496) listed on their death certificates; of these 2,554,959 decedents, only 1,106,614 (43.3%) had obstructive lung disease listed as the underlying cause of death. The age-adjusted mortality rate increased 47.3%, from 52.6 per 100,000 in 1979 to 77.5 per 100,000 in 1993. The age-adjusted mortality rate increased 17.1% among men, from 96.3% per 100,000 in 1979 to 112.8 per 100,000 in 1993, whereas this rate increased 126.1% among women, from 24.5 per 100,000 in 1979 to 55.4 per 100,000 in 1993. Over the study period, white males had the highest mortality rates (98.8 to 115.5 per 100,000), followed by black males (77.5 to 100.2 per 100,000), males of other races (38.1 to 58.6 per 100,000), white females (25.5 to 57.7 per 100,000), black females (14.9 to 38.5 per 100,000), and females of other races (10.9 to 20.9 per 100,000). We conclude that mortality related to obstructive lung disease is under-estimated in studies that look at only the underlying cause of death. Mortality rates of obstructive lung disease are starting to stabilize among men, but continue to increase among women, reflecting historical smoking trends in these populations.
我们利用美国国家卫生统计中心汇编的多死因死亡率档案中31314160例死亡者的死亡证明报告,分析了1979年至1993年间诊断为阻塞性肺病的死亡者的死亡率趋势。在所有死亡者中,有2554959例(8.2%)在其死亡证明上列出了阻塞性肺病的诊断(国际疾病分类第九版490至493.9、496);在这2554959例死亡者中,只有1106614例(43.3%)将阻塞性肺病列为根本死因。年龄调整后的死亡率上升了47.3%,从1979年的每10万人52.6例增至1993年的每10万人77.5例。男性的年龄调整后死亡率上升了17.1%,从1979年的每10万人96.3例增至1993年的每10万人112.8例,而女性的这一比率上升了126.1%,从1979年的每10万人24.5例增至1993年的每10万人55.4例。在研究期间,白人男性的死亡率最高(每10万人98.8至115.5例),其次是黑人男性(每10万人77.5至100.2例)、其他种族男性(每10万人38.1至58.6例)、白人女性(每10万人25.5至57.7例)、黑人女性(每10万人14.9至38.5例)和其他种族女性(每10万人10.9至20.9例)。我们得出结论,在仅关注根本死因的研究中,与阻塞性肺病相关的死亡率被低估了。阻塞性肺病的死亡率在男性中开始趋于稳定,但在女性中继续上升,这反映了这些人群过去的吸烟趋势。