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《精神疾病诊断与统计手册》第五版(DSM-5)与第四版(DSM-IV)在儿科患者尼古丁、酒精和大麻使用障碍诊断方面的一致性。

Concordance between DSM-5 and DSM-IV nicotine, alcohol, and cannabis use disorder diagnoses among pediatric patients.

作者信息

Kelly Sharon M, Gryczynski Jan, Mitchell Shannon Gwin, Kirk Arethusa, O'Grady Kevin E, Schwartz Robert P

机构信息

Friends Research Institute, Inc., 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA.

Friends Research Institute, Inc., 1040 Park Avenue, Suite 103, Baltimore, MD 21201, USA.

出版信息

Drug Alcohol Depend. 2014 Jul 1;140:213-6. doi: 10.1016/j.drugalcdep.2014.03.034. Epub 2014 Apr 13.

Abstract

BACKGROUND

The recently published Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) includes several major revisions to substance use diagnoses. Studies have evaluated the impact of these changes among adult samples but research with adolescent samples is lacking.

METHODS

525 adolescents (93% African American) awaiting primary care appointments in Baltimore, Maryland were recruited for a study evaluating a substance use screening instrument. Participants were assessed for DSM-5 nicotine, alcohol, and cannabis use disorder, DSM-IV alcohol and cannabis abuse, and DSM-IV dependence for all three substances during the past year using the modified Composite International Diagnostic Interview-2, Substance Abuse Module. Contingency tables examining DSM-5 vs. DSM-IV joint frequency distributions were examined for each substance.

RESULTS

Diagnoses were more prevalent using DSM-5 criteria compared with DSM-IV for nicotine (4.0% vs. 2.7%), alcohol (4.6% vs. 3.8%), and cannabis (10.7% vs. 8.2%). Cohen's κ, Somers' d, and Cramer's V ranged from 0.70 to 0.99 for all three substances. Of the adolescents categorized as "diagnostic orphans" under DSM-IV, 7/16 (43.8%), 9/29 (31.0%), and 13/36 (36.1%) met criteria for DSM-5 disorder for nicotine, alcohol, and cannabis, respectively. Additionally, 5/17 (29.4%) and 1/21 (4.8%) adolescents who met criteria for DSM-IV abuse did not meet criteria for a DSM-5 diagnosis for alcohol and cannabis, respectively.

CONCLUSIONS

Categorizing adolescents using DSM-5 criteria may result in diagnostic net widening-particularly for cannabis use disorders-by capturing adolescents who were considered diagnostic orphans using DSM-IV criteria. Future research examining the validity of DSM-5 substance use disorders with larger and more diverse adolescent samples is needed.

摘要

背景

最近发布的《精神疾病诊断与统计手册》第5版(DSM - 5)对物质使用障碍的诊断进行了多项重大修订。已有研究评估了这些变化对成人样本的影响,但缺乏针对青少年样本的研究。

方法

招募了525名在马里兰州巴尔的摩等待初级保健预约的青少年(93%为非裔美国人)参与一项评估物质使用筛查工具的研究。使用经过修改的《综合国际诊断访谈 - 2,物质滥用模块》,在过去一年中对参与者进行DSM - 5尼古丁、酒精和大麻使用障碍、DSM - IV酒精和大麻滥用以及对这三种物质的DSM - IV依赖的评估。针对每种物质,检查了用于检验DSM - 5与DSM - IV联合频率分布的列联表。

结果

与DSM - IV相比,使用DSM - 5标准诊断出的尼古丁(4.0%对2.7%)、酒精(4.6%对3.8%)和大麻(10.7%对8.2%)使用障碍更为普遍。对于所有三种物质,科恩κ系数、萨默斯d系数和克莱姆V系数范围为0.70至0.99。在DSM - IV下被归类为“诊断孤儿”的青少年中,分别有7/16(43.8%)、9/29(31.0%)和13/36(36.1%)符合DSM - 5尼古丁、酒精和大麻使用障碍的标准。此外,分别有5/17(29.4%)和1/21(4.8%)符合DSM - IV酒精和大麻滥用标准的青少年不符合DSM - 5酒精和大麻使用障碍的诊断标准。

结论

使用DSM - 5标准对青少年进行分类可能会导致诊断范围扩大——尤其是对于大麻使用障碍——因为会纳入那些使用DSM - IV标准被视为诊断孤儿的青少年。未来需要开展研究,以更大且更多样化的青少年样本检验DSM - 5物质使用障碍的有效性。

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