Mellor R, Chua S C, Boyce P
The University of Sydney, Sydney, NSW, Australia,
Arch Womens Ment Health. 2014 Aug;17(4):291-302. doi: 10.1007/s00737-014-0427-6. Epub 2014 May 3.
Research indicates that poor sleep quality is linked to and may precede depressive symptomatology in pregnancy, complicating screening for either condition. Pregnancy onset may also contribute to the development of sleep-disordered breathing (SDB). For the first time, the link between SDB and depression was examined in pregnancy. A total of 189 pregnant women completed the Edinburgh Postnatal Depression Scale (EPDS), Pittsburgh Sleep Quality Index (PSQI) for sleep quality and the Berlin Questionnaire for SDB. Women were also asked what they felt was the cause of their symptoms. PSQI-assessed poor sleep quality and self-perceived depression were strongly associated with EPDS scores of probable depression (X (2) 13.39; p < 0.001). Berlin-assessed risk of SDB was also associated with probable depression (X (2) 9.20 p < 0.01), though this was attenuated following multivariate analysis. There was a significant relationship between total PSQI score and the tendency for participants to attribute 'sleep-related causes' to their low mood (X (2) 20.78; p < 0.001). This study confirms the link between PSQI-assessed poor sleep quality and depressive symptoms in pregnancy, suggesting the two questionnaires assess the same or overlapping conditions. Although there was a relationship between probable depression and high risk SDB, the effect was attenuated after accounting for other depression risk factors, including body mass index (BMI).
研究表明，睡眠质量差与孕期抑郁症状相关，且可能先于抑郁症状出现，这使得对这两种情况的筛查变得复杂。怀孕也可能导致睡眠呼吸障碍（SDB）的发生。首次对孕期SDB与抑郁症之间的联系进行了研究。共有189名孕妇完成了爱丁堡产后抑郁量表（EPDS）、用于评估睡眠质量的匹兹堡睡眠质量指数（PSQI）以及用于评估SDB的柏林问卷。还询问了女性她们认为自己症状的原因是什么。PSQI评估的睡眠质量差和自我感知的抑郁与可能患抑郁症的EPDS评分密切相关（X（2）13.39；p < 0.001）。柏林问卷评估的SDB风险也与可能患抑郁症相关（X（2）9.20，p < 0.01），不过在多变量分析后这种相关性有所减弱。PSQI总分与参与者将“与睡眠相关的原因”归因于其情绪低落的倾向之间存在显著关系（X（2）20.78；p < 0.001）。这项研究证实了PSQI评估的睡眠质量差与孕期抑郁症状之间的联系，表明这两份问卷评估的是相同或重叠的情况。尽管可能患抑郁症与高风险SDB之间存在关联，但在考虑包括体重指数（BMI）在内的其他抑郁风险因素后，这种影响有所减弱。
