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尿失禁阴道吊带手术后网片侵蚀的危险因素。

Risk factors for mesh erosion after vaginal sling procedures for urinary incontinence.

作者信息

Kokanali M K, Doğanay M, Aksakal O, Cavkaytar S, Topçu H O, Özer İ

机构信息

Department of Obstetrics and Gynaecology, Dr. Zekai Tahir Burak Woman's Health Education and Research Hospital, Ankara, Turkey.

Department of Obstetrics and Gynaecology, Dr. Zekai Tahir Burak Woman's Health Education and Research Hospital, Ankara, Turkey.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2014 Jun;177:146-50. doi: 10.1016/j.ejogrb.2014.03.039. Epub 2014 Apr 13.

Abstract

OBJECTIVES

To identify risk factors for mesh erosion in women undergoing vaginal sling procedures for urinary incontinence with synthetic meshes, and to estimate the incidence of mesh erosion after these procedures.

STUDY DESIGN

Retrospective study of women who underwent vaginal sling procedures between January 2007 and January 2013. In total, 1439 consecutive women with stress urinary incontinence were investigated. Five hundred and sixty-six (39.3%) women underwent a tension-free vaginal tape (TVT) procedure and 873 (60.7%) women underwent a transobturator tape (TOT) procedure. All procedures were performed using meshes of the same type and size. Women who experienced mesh erosion were defined as cases, and women who were not re-admitted or identified with mesh erosion during the study period were defined as controls. Demographics, operative techniques and outcomes were taken from medical records. Multivariate regression identified the odds of mesh erosion.

RESULTS

Sixty-one of 1439 (4.2%) women were found to have mesh erosion in the postoperative period: 41 (67.2%) after TOT procedures and 20 (32.8%) after TVT procedures. The rate of mesh erosion was 4.7% in the TOT group and 3.5% in the TVT group, and this difference was significant (p<0.05). Mean age, body mass index, current smoking, menopausal status and diabetes mellitus were significantly higher among cases than controls. Univariate analysis showed that length of vaginal incision >2 cm, recurrent vaginal incision for postoperative complications, and previous pelvic organ prolapse or incontinence surgery were significant risk factors for erosion. Multivariate analysis demonstrated that older age, diabetes mellitus, current smoking, length of vaginal incision >2 cm, recurrent vaginal incision for postoperative complications, and previous pelvic organ prolapse or incontinence surgery were independent risk factors for mesh erosion.

CONCLUSIONS

Mesh erosion following vaginal sling procedures is a frustrating complication with relatively low incidence. It was found to occur more often after TOT procedures than TVT procedures. Older age, diabetes mellitus, smoking, length of vaginal incision >2 cm, recurrent vaginal incision for postoperative complications, and previous vaginal surgery for pelvic organ prolapse or incontinence increased the risk of mesh erosion. Identification of risk factors may enable surgeons to prevent or minimize this complication.

摘要

目的

确定接受合成网片治疗尿失禁的阴道吊带手术的女性发生网片侵蚀的危险因素,并估计这些手术后网片侵蚀的发生率。

研究设计

对2007年1月至2013年1月期间接受阴道吊带手术的女性进行回顾性研究。总共对1439例连续性压力性尿失禁女性进行了调查。566例(39.3%)女性接受了无张力阴道吊带术(TVT),873例(60.7%)女性接受了经闭孔吊带术(TOT)。所有手术均使用相同类型和尺寸的网片。经历网片侵蚀的女性被定义为病例组,在研究期间未再次入院或未发现有网片侵蚀的女性被定义为对照组。人口统计学、手术技术和结果均取自病历。多因素回归分析确定了网片侵蚀的几率。

结果

1439例女性中有61例(4.2%)在术后发生网片侵蚀:TOT手术后41例(67.2%),TVT手术后20例(32.8%)。TOT组网片侵蚀率为4.7%,TVT组为3.5%,差异有统计学意义(p<0.05)。病例组的平均年龄、体重指数、当前吸烟情况、绝经状态和糖尿病患病率均显著高于对照组。单因素分析显示,阴道切口长度>2 cm、因术后并发症再次进行阴道切口以及既往有盆腔器官脱垂或尿失禁手术史是侵蚀的重要危险因素。多因素分析表明,年龄较大、糖尿病、当前吸烟、阴道切口长度>2 cm、因术后并发症再次进行阴道切口以及既往有盆腔器官脱垂或尿失禁手术史是网片侵蚀的独立危险因素。

结论

阴道吊带手术后的网片侵蚀是一种令人沮丧的并发症,发生率相对较低。发现TOT手术后比TVT手术后更常发生。年龄较大、糖尿病、吸烟、阴道切口长度>2 cm、因术后并发症再次进行阴道切口以及既往有盆腔器官脱垂或尿失禁的阴道手术会增加网片侵蚀的风险。识别危险因素可能使外科医生能够预防或尽量减少这种并发症。

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